1. C.O.S. Sorzano. Analisis Espectral de Peliculas Mamograficas. Univ. Malaga (1997)
2. J.M.Carazo, C.O.S. Sorzano, E. Rietzel, R.R. Schroder, R. Marabini. Discrete Tomography in Electron Microscopy . Discrete Tomography: Foundations, Algorithms and Applications, 405-416. Ed. Birkhauser (1999).
3. C.O.S. Sorzano. Generador automatico de interfaces graficos de usuario. Univ. Malaga (2000)
4. C.O.S. Sorzano. Algoritmos iterativos de tomografia tridimensional en microscopia electronica de transmision . Univ. Politecnica de Madrid (2002)
5. S. Jonic, P. Thevenaz, C.O.S. Sorzano, M. Unser. Spline-based 3D-to-2D image registration for image-guided surgery and 3D electron microscopy. Biophotonics for life sciences and medicine. Eds. M. Faupel, P. Smiegielski, A. Brandenburg, J. Fontaine. Fontis Media, 2005.
6. J.M. Carazo, G.T. Herman, C.O.S. Sorzano, R. Marabini. Algorithms for three-dimensional reconstruction from imperfect projection data provided by electron microscopy. Electron Tomography: methods for three-dimensional visualization of structures in the cell. Ed. J. Frank. Springer, 2nd edition, 2006.
7. A. Otero Quintana, C.O.S. Sorzano, R. Garcia Garcia. Aprenda a programar en C mediante ejemplos. Ed. Torculo, 2008.
8. S. Jonic, C.O.S. Sorzano. Splines for bioimaging. Optical and Digital Image Processing: Fundamentals and Applications. Eds. G. Cristobal, P. Schelkens, H. Thienpont. Wiley VCH, pp 119-134 (2011) Original full chapter
9. C.O.S. Sorzano, J. M. de la Rosa Trevin, J. Oton, J. J. Vega, J. Cuenca, A. Zaldivar-Peraza, J. Gomez-Blanco, J. Vargas, A. Quintana, R. Marabini, J. M. Carazo. Semiautomatic, high-throughput, high-resolution protocol for three-dimensional reconstruction of Single Particles in Electron Microscopy. Nanoimaging: Methods and Protocols. Methods in Molecular Biology, 950: 171-193. Eds. Alioscka Sousa, Michael Kruhlak. Humana Press. (2012)
10. Z. Devaux, C.O.S. Sorzano, S. Jonic. Processing of Transmission Electron Microscopy Images for Single-Particle Analysis of Macromolecular Complexes. In P. M. Conn (Ed.), Laboratory Methods in Cell Biology (pp. 295\96310). Elsevier Inc. (2012)
11. C.O.S. Sorzano, R. Marabini, J. Vargas, J. Oton, J. Cuenca-Alba, A. Quintana, J.M. de la Rosa-Trevin, J.M. Carazo. Interchanging geometry information in electron microscopy single particle analysis: mathematical context for the development of a standard. Computational Methods for Three-Dimensional Microscopy Reconstruction: 7-42 (2014) (preprint)
12. J. Oton, C.O.S. Sorzano, F.J. Chichon, J.L. Carrascosa, J.M. Carazo, R. Marabini. Soft X-ray Tomography Imaging for Biological Samples. Computational Methods for Three-Dimensional Microscopy Reconstruction: 187-220 (2014) (preprint)
13. C.O.S. Sorzano. A signal processing approach to pharmacokinetics, pharmacodynamics and biopharmaceutics data analysis. Univ. San Pablo CEU (2015)
14. C.O.S. Sorzano. Panorama de investigacion en Ingenieria Biomedica 2015 (2015)
15. A. Verguet, C. Messaoudi, C.O.S. Sorzano, S. Marco. Alignment of tilt series. Cellular Imaging: Electron Tomography and Related Techniques: 183-207 (2018)
16. C.O.S. Sorzano, M. Parkinson. Statistical design for animal research. (2018)
17. C.O.S. Sorzano, A. Jiménez-Moreno, D. Maluenda, E. Ramírez-Aportela, M. Martínez, A. Cuervo, R. Melero, P. Conesa, R. Sánchez-García, D. Strelak, J. Filipovic, E. Fernández-Giménez, F. de Isidro-Gómez, D. Herreros, P. Conesa, L. del Caño, Y. Fonseca, J. Jiménez de la Morena, J.R. Macías, P. Losada, R. Marabini, J.M. Carazo. Image processing in Cryo-Electron Microscopy of Single Particles: the power of combining methods. Methods in Molecular Biology 2305: Structural Proteomics, 3rd ed: 257-289 (2021)
18. C.O.S. Sorzano. Panorama de investigacion en Ingenieria Biomedica 2020 (2020)
19. M. Parkinson, C.O.S. Sorzano. Why do we need a statistical experiment design? Experimental Design and Reproducibility in Preclinical Animal Studies, Eds. J.M. Sánchez-Morgado, A. Bronstad (2021)
20. M. Parkinson, C.O.S. Sorzano. Statistical tests and Sample size calculations Experimental Design and Reproducibility in Preclinical Animal Studies, Eds. J.M. Sánchez-Morgado, A. Bronstad (2021)
21. M. Parkinson, C.O.S. Sorzano. Design of experiments Experimental Design and Reproducibility in Preclinical Animal Studies, Eds. J.M. Sánchez-Morgado, A. Bronstad (2021)
22. F.P. de Isidro-Gómez, J.L. Vilas, E. Fernández-Giménez, O. Laurizika, D. Marchán, M. Iceta, D. Herreros, P. Conesa, Y.C. Fonseca, J. Jiménez de la Morena, A. Cuervo, P. Losana, C.O.S. Sorzano, J.M. Carazo. Validation methods in cryo-electron tomography. (2023)
23. C.O.S. Sorzano. Statistical experiment design for animal research. OSF Preprints: osf.io/e9s25 (2023)

1. C.O.S.Sorzano, R.Marabini, N.Boisset, E.Rietzel, R.Schroder, G.T.Herman, J.M.Carazo. The effect of overabundant projection directions on 3D reconstruction algorithms. Journal of Structural Biology, 133 (2,3), 108-118 (2001)
2. C.O.S.Sorzano, J.M.Carazo, O.Trelles. Command line interfaces can be efficiently brought to graphics: COLIMATE (the COmmand LIne MATE) Software: Practice & Experience 32 (9): 873-887 (2002)
3. J.A. Velazquez-Muriel, C.O.S.Sorzano, J.J. Fernandez, J.M. Carazo. A method for estimating the CTF in electron microscopy based on ARMA models and parameter adjusting. Ultramicroscopy 96, 1:17-35. (2003, cover article)
4. J. Zubelli, R. Marabini, C.O.S.Sorzano, G.T. Herman. Three-dimensional reconstruction by Chahine's method from electron microscopic projections corrupted by instrumental aberrations. Inverse Problems 19: 933-949 (2003)
5. M. Gomez-Lorenzo, M. Valle, J. Frank, C. Gruss, C.O.S.Sorzano, X. S. Chen, L.E. Donate, J.M. Carazo. Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication. EMBO Journal 22: 6205-6213 (2003)
6. R. Marabini, C.O.S.Sorzano, S. Matej, J.J. Fernandez, J.M. Carazo, G.T. Herman. 3D reconstruction of 2D crystals. IEEE Trans. on Image Processing 13: 549-561 (2004)
7. C.O.S.Sorzano, R. Marabini, G.T. Herman, Y. Censor, J.M. Carazo. Transfer function restoration in 3D electron microscopy via iterative data refinement. Physics in Medicine & Biology 49: 509-522 (2004)
8. C.O.S.Sorzano, S. Jonic, C. El-Bez, J.M. Carazo, S. De Carlo, P. Thevenaz, M. Unser. A multiresolution approach to orientation assignment in 3-D electron microscopy of single particles. Journal of Structural Biology 146(3): 381-392 (2004, cover article)
9. C.O.S.Sorzano, L.G. de la Fraga, R. Clackdoyle, J.M.Carazo. Normalizing projection images: a study of image normalizing procedures for single particle three-dimensional electron microscopy. Ultramicroscopy 101(2-4): 129-138 (2004)
10. J.R.Bilbao, C.O.S.Sorzano, I. Garcia, J.J. Fernandez. Phan3D: Design of biological phantoms in 3D electron microscopy. Bioinformatics 20: 3286-3288 (2004)
11. C.O.S.Sorzano, R. Marabini, J. Velazquez-Muriel, J.R. Bilbao-Castro, S.H.W. Scheres, J.M. Carazo, A. Pascual-Montano. XMIPP: a new generation of an open-source image processing package for Electron Microscopy. Journal of Structural Biology 148: 194-204 (2004)
12. C.O.S.Sorzano, P. Thevenaz, M. Unser. Elastic registration of biological images using vector-spline regularization. IEEE Trans. on Biomedical Engineering, 52: 652-663 (2005)
13. M. Unser, C.O.S.Sorzano, P. Thevenaz, S. Jonic, C. El-Bez, S. De Carlo, J. Conway, B. L. Trus. Spectral Signal-to-Noise Ratio and resolution assessment of 3D reconstructions. Journal of Structural Biology, 149: 243-255 (2005)
14. J. Velazquez-Muriel, C.O.S.Sorzano, S.H.W. Scheres, J.M. Carazo. SPI-EM: Towards a tool for predicting the CATH superfamily in 3D-EM maps. Journal of Molecular Biology, 345: 759-771 (2005)
15. S. Jonic, C.O.S.Sorzano, P. Thevenaz, C. El-Bez, S. De Carlo, M. Unser. Spline-Based image-to-volume registration for three-dimensional electron microscopy. Ultramicroscopy,  103:  303-317 (2005)
16. S.H.W. Scheres, M. Valle, R. Nuñez, C.O.S. Sorzano, R. Marabini, G.T. Herman, J.M Carazo. Maximum-likelihood multi-reference refinement for electron microscopy images. Journal of Molecular Biology, 348: 139-149 (2005)
17. C.O.S.Sorzano, R. Marabini, G.T. Herman, J.M. Carazo. Multiobjective algorithm parameter optimization using multivariate statistics. Pattern Recognition, 38: 2587-2601 (2005)
18. C.O.S.Sorzano, E. Ortiz, M. Lopez, J. Rodrigo. Improved Bayesian image denoising based on wavelets with applications to Electron Microscopy. Pattern Recognition, 39: 1205-1213 (2006)
19. J.J. Fernandez, C.O.S.Sorzano, R. Marabini, J.M. Carazo. Image processing and three-dimensional reconstruction in electron microscopy of biological specimens. IEEE Signal Processing Magazine, 23(3): 89-94 (2006)
20. C.O.S.Sorzano, R. Marabini, A. Pascual-Montano, S.H.W. Scheres, J.M. Carazo. Optimization problems in electron microscopy of single particles. Annals of Operations Research, 148: 133-165 (2006)
21. I. Arganda-Carreras,  C.O.S. Sorzano, R. Marabini, J.M. Carazo, C. Ortiz-de-Solorzano, J. Kybic. Consistent and elastic registration of histological sections using vector-spline regularization. Lecture Notes in Computer Science, 4241: 85-95 (2006)
22. S. Jonic, C.O.S.Sorzano, M. Cottevieille, E. Larquet, N. Boisset.  A novel method for improvement of visualization of power spectra for classification of cryo-electron micrographs and their local areas. Journal of Structural Biology, 157: 156-167 (2007)
23. C.O.S. Sorzano, S. Jonic, M. Cottevieille, E. Larquet, N. Boisset, S. Marco. 3D Electron microscopy of biological nanomachines: principles and applications. European Biophysics Journal, 36: 995-1013 (2007)
24. C. Messaoudi, T. Boudier, C.O.S. Sorzano, S. Marco. TomoJ: tomography software for 3D reconstruction in transmission electron tomography. BMC Bioinformatics 8, 288 (2007)
25. C.O.S. Sorzano, S. Jonic, R. Nuñez, N. Boisset, J.M. Carazo. Fast, robust and accurate determination of transmission electron microscopy contrast transfer function. Journal Structural Biology 160: 249-262 (2007) [Corrigendum]
26. C.O.S.Sorzano, J. Velazquez-Muriel, R. Marabini, G.T. Herman, J.M. Carazo. Volumetric restrictions in single particle 3DEM reconstruction. Pattern Recognition 41: 616-626 (2008)
27. C.O.S. Sorzano, S. I. Arganda-Carreras, P. Thevenaz, A. Beloso, G. Morales, I. Valdes, C. Perez-Garcia, C. Castillo, E. Garrido, M. Unser. Elastic Image Registration of 2D gels for differential and repeatability studies. Proteomics 8: 62-65 (2008)
28. S. Jonic, C.O.S. Sorzano, N. Boisset. Comparison of single-particle analysis and electron tomography approaches: an overview. Journal of Microscopy, 232: 562-579 (2008)
29. S. H. W. Scheres, R. Nuñez-Ramirez, C.O.S. Sorzano, J.M. Carazo, R. Marabini. Image processing for electron microscopy single-particle analysis using Xmipp. Nature protocols, 3: 977-990 (2008)
30. A. Beuchat, P. Thevenaz, M. Unser, T. Ebner, A. Senn, F. Urner, M. Germond, C.O.S. Sorzano. Quantitative morphometrical characterization of human pronuclear zygotes. Human Reproduction, 23: 1983-1992 (2008)
31. J.R. Bilbao-Castro, R. Marabini, C.O.S Sorzano, I. Garcia, J.M. Carazo. Desktop supercomputing for 3D-EM: structure determination using ART with blobs. Journal of Structural Biology, 165: 19-26 (2009)
32. A. Iriarte Ruiz, C.O.S. Sorzano, J. L. Rubio, J. M. Carazo, R. Marabini. A theoretical model for EM-ML reconstruction algorithms applied to rotating PET scanners. Physics in Medicine and Biology, 54: 1909-1934 (2009)
33. C.O.S. Sorzano, A. Otero, E.M. Olmos, J.M. Carazo. Error analysis in the determination of the electron microscopical contrast transfer function parameters from experimental power spectra. BMC Structural Biology, 9: 18 (2009)
34. C.O.S. Sorzano, C. Messaoudi, M. Eibauer, J.R. Bilbao-Castro, R. Hegerl, S. Nickell, S. Marco, J.M. Carazo. Marker-free image registration of electron tomography tilt-series. BMC Bioinformatics, 10: 124 (2009)
35. C.O.S. Sorzano, E. Recarte, M. Alcorlo, J.R. Bilbao-Castro, C. San-Martin, R. Marabini, J.M. Carazo. Automatic particle selection from electron micrographs using machine learning techniques. Journal of Structural Biology, 167: 252-260 (2009)
36. C.O.S. Sorzano, J.R. Bilbao-Castro, Y. Shkolnisky, M. Alcorlo, R. Melero, G. Caffarena-Fernandez, M. Li, G. Xu, R. Marabini, J.M. Carazo. A clustering approach to multireference alignment of single-particle projections in electron microscopy. J. Structural Biology 171: 197-206 (2010)
37. J.L. Najera, C.E. Gomez, J. Garcia-Arriaza, C.O.S. Sorzano, M. Esteban. Insertion of Vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens. PLOS One 5, e11406 (2010)
38. J. Garcia-Arriaza, J.L. Najera, C.E. Gomez, C.O.S. Sorzano, M. Esteban. Immunogenic profiling in mice of a candidate HIV/AIDS vaccine (MVA-B) expressing four HIV-1 antigens and potentiation by specific gene deletions. PLOS One 5, e12395 (2010)
39. J.R. Bilbao-Castro, C.O.S. Sorzano, J.J. Fernandez, I. Garcia. XMSF: Structure-preserving noise reduction and pre-segmentation in microscope tomography. Bioinformatics, 26: 2786-2787 (2010)
40. I. Arganda-Carreras, C.O.S. Sorzano, P. Thevenaz, A. Muñoz-Barrutia, J. Kybic, R. Marabini, J. M. Carazo, C. Ortiz-de-Solorzano. Non-rigid consistent registration of 2D image sequences. Physics in Medicine and Biology, 55: 6215-6242 (2010)
41. C. Calabia-Linares, M. Perez-Martinez, N. Martin-Cofreces, M. Alfonso-Perez, C. Gutierrez-Vazquez, M. Mittelbrunn, S. Ibiza, F.R. Urbano-Olmos, C. Aguado-Ballano, C.O.S. Sorzano, F. Sanchez-Madrid, E. Veiga. Clathrin drives actin accumulation at the immunological synapse. J. Cell Science, 124: 820-830 (2011)
42. E. Rincon, J. Saez, S. Gharbi, C.O.S. Sorzano, Y.R. Carrasco, I. Merida. Dynamics of sorting nexin 27 translocation in activated T cells. J. Cell Science, 124: 776-788 (2011)
43. M. Li, G. Xu, C.O.S. Sorzano, F. Sun, C. Bajaj. Single-Particle Reconstruction Using L2-Gradient Flow. J. Structural Biology, 176: 259-267 (2011)
44. J. Vargas, J.A. Quiroga, C.O.S. Sorzano, J.C. Estrada, J.M. Carazo.  Two-step interferometry by a regularized optical flow algorithm. Optics Letters 36, 3485-3487 (2011)
45. C.E. Gomez, J.L. Najera, B. Perdiguero, J. Garcia-Arriaza, C.O.S. Sorzano, V. Jimenez, R. Gonzalez-Sanz, J.L. Jimenez, M.A. Muñoz-Fernandez, J.C. Lopez Bernaldo de Quiros, A.C. Guardo, F. Garcia, J. Gatell, M. Plana, M. Esteban. The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in humans triggers robust, polyfunctional and selective effector memory T cell responses to HIV-1 antigens. J. Virology 85: 11468-11478 (2011)
46. J. Garcia-Arriaza, J.L. Najera, C.E. Gomez, N. Tewabe, C.O.S. Sorzano, T. Calandra, T. Roger, M. Esteban. A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-specific T-cell Responses. Plos ONE, 6: e24244 (2011)
47. A. G. Goodman, P. P. Heinen, S. Guerra, A. Vijayan, C.O.S. Sorzano, C.E. Gomez, M. Esteban.  A human multi-epitope recombinant vaccinia virus as a universal T-cell vaccine candidate against influenza virus. Plos ONE, 6: e25938 (2011)
48. J. Vargas, J.A. Quiroga, C.O.S. Sorzano, J.C. Estrada, J.M. Carazo. Two-step demodulation based on Gram-Schmidt orthonormalization method. Optics Letters, 37: 443-445 (2012)
49. J. Oton, C.O.S. Sorzano, E. Pereiro, J. Cuenca, R. Navarro, R. Marabini, J.M. Carazo. Image formation in cellular X-ray microscopy. J. Structural Biology, 178: 29-37 (2012)
50. C.E. Gomez, B. Perdiguero, J.L. Najera, C.O.S.Sorzano, V. Jimenez, R. Gonzalez-Sanz, M. Esteban. Removal of vaccinia virus genes that block interferon type I and II pathways improves adaptive and memory responses of the HIV/AIDS vaccine candidate NYVAC-C in mice. J. Virology, 86: 5026-5038 (2012)
51. A. Vijayan, C.E. Gomez, D.A. Espinosa, A.G. Goodman, L. Sanchez, C.O.S. Sorzano, F. Zavala, M. Esteban. Adjuvant-like effect of vaccinia virus 14K protein: A Case Study with Malaria Vaccine based on the Circumsporozoite Protein. J. Immunology, 188: 6407-6417 (2012)
52. L. Sanchez-Sampedro, C.E. Gomez, E. Mejias-Perez, C.O.S. Sorzano, M. Esteban. High quality long-term CD4+ and CD8+ effector memory populations stimulated by DNA-LACK/MVA-LACK regimen in Leishmania major BALB/c model of infection. PLOS One 7(6):e38859 (2012)
53. J. Vargas, J. Antonio Quiroga, C.O.S. Sorzano, J. C. Estrada, M. Servin. Multiplicative phase-shifting interferometry using optical flow. Applied Optics, 51: 5903-5908 (2012)
54. J. Vargas, R. Restrepo, J.C. Estrada, C.O.S. Sorzano, J.M. Carazo. Shack-Hartmann centroid detection using the Spiral Phase Transform. Applied Optics, 51: 7362-7367 (2012)
55. A. Patwardhan, J.M. Carazo, B. Carragher, R. Henderson, J.B. Heymann, E. Hill, G. J. Jensen, I. Lagerstedt, C.L. Lawson, S.J. Ludtke, D. Mastronarde, W. Moore, A. Roseman, P. Rosenthal, C.O.S. Sorzano, E. Sanz-Garcia, S.H.W. Scheres, S. Subramaniam, J. Westbrook, M. Winn, J. Swedlow, G.J. Kleywegt. Data-management Challenges in 3D Electron Microscopy. Nature Structure & Molecular Biology, 19: 1203-1207 (2012).
56. B. Perdiguero, C.E. Gomez, J.L. Najera, C.O.S. Sorzano, J. Delaloye, R. Gonzalez-Sanz, V. Jimenez, T. Roger, T. Calandra, G. Pantaleo, M. Esteban. Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens. PLOS One, 7: e48524 (2012)
57. J. Vargas, C.O.S. Sorzano, J.C. Estrada, J.M. Carazo. Generalization of the Principal Component Analysis algorithm for interferometry. Optics Communications, 286: 130-134 (2013)
58. J. Vargas, C.O.S. Sorzano, J. Oton, R. Marabini, S. Jonic, J.M. de la Rosa-Trevin, J.M. Carazo. FASTDEF: Fast defocus and astigmatism estimation for Transmission Electron Microscopy. J. Structural Biology, 181: 136-148 (2013)
59. J. Vargas, C.O.S. Sorzano. Quadrature Component Analysis for interferometry. Optics and Lasers in Engineering, 51: 637-641 (2013)
60. J. Vargas, C.O.S. Sorzano, J.A. Quiroga, J.C. Estrada, J. M. Carazo. Fringe pattern denoising by image dimensionality reduction. Optics and Lasers in Engineering, 51: 921-928 (2013)
61. E. Gonzalez-Grandio, C. Poza-Carrion, C.O.S. Sorzano, P. Cubas. BRANCHED1 promotes axillary bud dormancy in response to shade in Arabidopsis. Plant Cell, 25: 834-850 (2013)
62. C.E. Gomez, B. Perdiguero, L. Mingorance, J. Garcia-Arriaza, A. Vandermeeren, M.V. Cepeda, C.O.S. Sorzano, M. Esteban. High, broad, polyfunctional and durable T cell immune responses induced in mice by a novel hepatitis C virus (HCV) vaccine candidate based on MVA expressing the near full-length HCV genome (MVA-HCV). J. Virology, 87: 7282-7300 (2013)
    
63. R. Marabini, J.R. Macias, J. Vargas, A. Quintana, C.O.S. Sorzano, J.M. Carazo. Developing of three new tools for organizing and sharing information in three-dimensinal electron microscopy. Acta Crystallographica D, 69: 695-700 (2013)
64. T. Bharat, D. Zbaida, M. Eisenstein, Z. Frankenstein, T. Mehlman, L. Weiner, C.O.S. Sorzano, Y. Barak, S. Albeck, J.A.G. Briggs, S.G. Wolf, M. Elbaum. Variable internal flexibility characterizes the helical capsid formed by Agrobacterium VirE2 protein on single-stranded DNA. Structure, 21: 1158-1167 (2013)
65. R. Nogales, S. Jonic, F. Tama, A.A. Arteni, D. Tabas-Madrid, M. Vazquez, A. Pascual-Montano, C.O.S. Sorzano. 3DEM Loupe: analysis of macromolecular dynamics using structures from electron microscopy. Nucleic Acids Research 41: W363-367 (2013)
    
66. C.O.S. Sorzano, A. Pascual-Montano, A. Sanchez de Diego, C. Martinez-A, K.H.M. van Wely. A perspective on chromothripsis: It's breakage-fusion-bridge all over again. Cell Cycle, 12: 2016-2023 (2013)
67. C. Messaoudi, N. Aschman, M. Cunha, T. Oikawa, C.O.S. Sorzano, S. Marco. EFTEM-TomoJ: 3D chemical mapping by EFTEM including SNR improvement by PCA and volume improvement by noise suppression during the ART reconstruction process. Microscopy & Microanalysis, 19: 1669-1677 (2013)
    
68. J. Vargas, J.M. Carazo, C.O.S. Sorzano. Error analysis of the Principal Component Analysis demodulation algorithm. Applied Physics B: Lasers and Optics: 1-10 (2013)
    
69. T.M. Zotes, R. Spada, V. Mulens, S. Perez-Yague, C.O.S. Sorzano, K. Okkenhaug, B, A.C. Carrera, D.F. Barber. PI3K p110? Is Expressed by gp38?CD31+ and gp38+CD31+ Spleen Stromal Cells and Regulates Their CCL19, CCL21, and LT?R mRNA Levels. PLOS One, 8(8): e72960 (2013)
    
70. V. Abrishami, A. Zaldivar-Peraza, J.M. de la Rosa-Trevin, J. Vargas, J. Oton, R. Marabini, Y. Shkolnisky, J.M. Carazo, C.O.S. Sorzano. A pattern matching approach to the automatic selection of particles from low-contrast electron micrographs. Bioinformatics, 29: 2460-2468 (2013)
71. J. Vargas, V. Abrishami, R. Marabini, J.M. de la Rosa-Trevin, A. Zaldivar, J.M. Carazo, C.O.S. Sorzano. Particle quality assessment and sorting for automatic and semiautomatic particle-picking techniques. J. Structural Biology, 183: 342-353 (2013)
72. A. Caceres, B. Perdiguero, C.E. Gomez, M.V. Cepeda, C. Caelles, C.O.S. Sorzano, M. Esteban. Involvement of the cellular phosphatase DUSP1 in Vaccinia Virus infection. PLOS Pathogens, 9: e1003719 (2013)
    
73. J.M. De la Rosa-Trevin, J. Oton, R. Marabini, A. Zaldivar-Peraza, J. Vargas, J.M. Carazo, C.O.S. Sorzano. Xmipp 3.0: An improved software suite for image processing in electron microscopy. J. Structural Biology, 184: 321-328 (2013)
74. M. Di Pilato, E. Mejias-Perez, C.E. Gomez, B. Perdiguero, C.O.S. Sorzano, M. Esteban. New vaccinia virus promoter as candidate for future vaccine. J. General Virology, 94: 2771-2776 (2013).
75. J. Garcia-Arriaza, P. Arnaez, C.E. Gomez, C.O.S. Sorzano, M. Esteban. Improving adaptive and memory immune responses of an HIV/AIDS vaccine candidate MVA-B by deletion of vaccinia virus genes (C6L and K7R) blocking interferon signaling pathways. PLOS One, 8: e66894 (2013)
76. B. Perdiguero, C.E. Gomez, M. Di Pilato, C.O.S. Sorzano, J. Delaloye, T. Roger, T. Calandra, G. Pantaleo, M. Esteban. Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity of the HIV/AIDS vaccine candidate NYVAC-C. PLOS One, 8: e74831 (2013)
77. Q. Jin, C.O.S. Sorzano, J.M. de la Rosa-Trevin, J.R. Bilbao-Castro, R. Nuñez-Ramirez, O. Llorca, F. Tama, S. Jonic. Iterative elastic 3D-to-2D alignment method using normal modes for studying structural dynamics of large macromolecular complexes. Structure, 22: 496-506 (2014)
78. J. Garcia-Arriaza, V. Cepeda, D. Hallengard, C.O.S. Sorzano, B. Kummerer, P. Liljestrom, M. Esteban. A novel poxvirus-based vaccine (MVA-CHIKV) is highly immunogenic and protects mice against Chikungunya infection. J. Virology, 88: 3527-3547 (2014).
79. J. Garcia-Arriaza, C.E. Gomez, C.O.S. Sorzano, M. Esteban. Deletion of the vaccinia virus N2L gene encoding an inhibitor of IRF3 improves the immunogenicity of MVA expressing HIV-1 antigens. J. Virology, 88: 3392-3410 (2014)
80. G. Morlino, O. Barreiro, F. Baixauli, J. Robles-Valero, J.M. Gonzalez-Granado, R. Villa-Bellosta, J.Cuenca, C.O.S. Sorzano, E. Veiga, N.B. Martin-Cofreces, F. Sanchez-Madrid. Miro-1 links mitochondria and microtubule dynein motors to control lymphocyte migration and polarity. Molecular and Cell Biology, 34: 1412-1426 (2014)
81. P.F. Fribourg, M. Chami, C.O.S. Sorzano, F. Gubellini, R. Marabini, S. Marco, J.M. Jault, D. Levy. 3D cryo-electron reconstruction of BmrA, a bacterial multidrug ABC transporter in an inward facing conformation and in a lipidic environment. J. Mol. Biol, 426: 2059.2069 (2014)
    
82. J. Vargas, A.L. Alvarez-Cabrera, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Efficient initial volume determination from electron microscopy images of single particles. Bioinformatics, 30: 2891-2898 (2014)
    
83. C.O.S. Sorzano, J. Vargas, G. Caffarena-Ruiz, A. Iriarte-Ruiz. Comparing scientific performance among equals. Scientometrics, 101: 1731-1745 (2014)
    
84. Y. Chen, S. Pfeffer, J.J. Fernandez, C.O.S. Sorzano, F. Foerster. Autofocused 3D Classification of cryo-electron subtomograms. Structure, 22: 1528-1537 (2014)
    
85. C.O.S. Sorzano, J.M. de la Rosa Trevin, F. Tama, S. Jonic. Hybrid Electron Microscopy Normal Mode Analysis graphical interface and protocol. J. Structural Biology, 188: 134-141 (2014)
    
86. D. Tabas-Madrid, A. Muniategui, I. Sanchez-Caballero, D. Martinez-Herrera, C.O.S. Sorzano, A. Rubio, A. Pascual-Montano. Improving miRNA-mRNA Interaction Predictions. BMC Genomics 15 (Suppl. 10): S2 (2014)
    
87. B. Perdiguero, C.E. Gomez, V. Cepeda, L. Sanchez-Sampedro, J. Garcia-Arriaza, E.Mejias-Perez, V. Jimenez, C. Sanchez, C.O.S. Sorzano, J.C. Oliveros, J. Delaloye, T. Roger, T. Calandra, B. Asbach, R. Wagner, K. Kibler, B. Jacobs, G. Pantaleo, M. Esteban. Virological and immunological characterization of novel NYVAC-based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as VLPs. J. Virology, 89: 970-988 (2015)
    
88. C.O.S. Sorzano, J. Vargas, J.M. de la Rosa-Trevin, J. Oton, A.L. Alvarez-Cabrera, V. Abrishami, E. Sesmero, R. Marabini, J.M. Carazo. A Statistical approach to the initial volume problem in Single Particle Analysis by Electron Microscopy. J. Structural Biology, 189: 213-219 (2015)
    
89. J. Oton, C.O.S. Sorzano, R. Marabini, E. Pereiro, J.M. Carazo. Measurement of the modulation transfer function of an X-ray microscope based on multiple Fourier orders analysis of a Siemens star. Optics Express, 23: 9567-9572 (2015)
    
90. C.O.S. Sorzano, M.A. Perez de la Cruz-Moreno, J. Burguet-Castell, C. Montejo, A. Aguilar Ros. Cost-constrained optimal sampling for system identification in pharmacokinetics applications with population priors and nuisance parameters. J. Pharmaceutical Sciences, 104: 2103-2109 (2015)
91. V. Abrishami, J. Vargas, Y. Cheng, X. Li, R. Marabini, C.O.S. Sorzano, J.M. Carazo. Alignment of direct detector device micrographs using a robust optical flow approach. J. Structural Biology, 189: 163-176 (2015)
92. M. Di Pilato, E. Mejias-Perez, M. Zonca, B. Perdiguero, C.E. Gomez, M. Trakala, J. Nieto, J.L. Najera, C.O.S. Sorzano, L. Planelles, M. Esteban. NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses. Proc. Natl. Acad. Sciences, 112: E1333-E1342 (2015)
    
93. C.O.S. Sorzano, J. Vargas, J. Oton, V. Abrishami, J.M. de la Rosa-Trevin, S. del Riego, A. Fernandez-Alderete, C. Martinez-Rey, R. Marabini, J.M. Carazo. Fast and accurate conversion of atomic models into electron density maps. AIMS Biophysics, 2: 8-20 (2015)
94. J. Segura, C.O.S. Sorzano, J. Cuenca-Alba, P. Aloy, J.M. Carazo. Inferring protein-protein domain interactions using neighborhood cohesiveness. Bioinformatics, 31: 2545-2552 (2015)
95. K.M. Lam, C.O.S. Sorzano, Z. Zhang, P. Campisi. A competition for undergraduate students: The IEEE Signal Processing Cup, Part 1. IEEE Signal Processing Magazine, 32: 123-125 (2015)
    
96. R. Marabini, B. Carragher, S. Chen, J. Chen, A. Cheng, K.H. Downing, J. Frank, R.A. Grasucci, J.B. Heymann, W. Jiang, S. Jonic, H. Liao, S.J. Ludtke, S. Patwari, A.L. Piotrowski, A. Quintana, C.O.S. Sorzano, H. Stahlberg, J. Vargas, N.R. Voss, W. Chiu, J.M. Carazo. CTF Challenge: Result summary. J. Structural Biology, 190: 348-359 (2015)
    
97. J. Setoain, M. Franch, M. Martinez, D. Tabas-Madrid, C.O.S. Sorzano, A. Bakker, E. Gonzalez-Couto, J. Elvira, A. Pascual-Montano. NFFinder: an online bioinformatics tool for searching similar transcriptomics experiments in the context of drug repurposing. Nucleic Acids Research, 43: W193-W199 (2015)
98. M. Di Pilato, L. Sanchez-Sampedro, E. Mejias-Perez, C.O.S. Sorzano, M. Esteban. Modification of promoter spacer length in vaccinia virus as a strategy to control the antigen expression . J. General Virology, 96: 2360-2371 (2015)
99. J.M. Carazo, C.O.S. Sorzano, J. Oton, R. Marabini, J. Vargas. Three-dimensional reconstruction methods in transmission electron microscopy. Archives of Biochemistry and Biophysics, 581: 39-48 (2015)
100. C.O.S. Sorzano. Undergraduate Students Compete in the IEEE Signal Processing Cup: Part 2. IEEE Signal Processing Magazine, 32: 109-111 (2015)
101. V. Abrishami, J.R. Bilbao-Castro, J. Vargas, R. Marabini, J.M. Carazo, C.O.S. Sorzano. A fast iterative convolution-based weighting approach for direct Fourier three-dimensional reconstruction. Ultramicroscopy, 157: 79-87 (2015)
102. A. Vijayan, J. Garcia-Arriaza, S. C. Raman, J.J. Conesa, F.J. Chichon, C.O.S. Sorzano, J.L. Carrascosa, M. Esteban. A chimeric HIV-1 gp120 fused with vaccinia virus 14K (A27) protein as an HIV immunogen. PLOS One, 10:e0133595 (2015)
103. C.O.S. Sorzano, M. Alcorlo, J.M. de la Rosa-Trevin, R. Melero, I. Foche, A. Zaldivar-Peraza, L. del Cano, J. Vargas, V. Abrishami, J. Oton, R. Marabini, J.M. Carazo. Cryo-EM and the elucidation of new macromolecular structures: Random Conical Tilt revisited. Scientific Reports, 5: 14290 (2015)
104. C.E. Gomez, B. Perdiguero, J. Garcia-Arriaza, M.V. Cepeda, C.O.S. Sorzano, B. Mothe, J.L. Jimenez, M.A. Muñoz-Fernandez, J.M. Gatell, J.C. Lopez Bernaldo de Queiros, C. Brander, F. Garcia, M. Esteban. A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-infected Subjects on HAART. PLOS One 10:e0141456 (2015)
     
105. S. Jonic, C.O.S. Sorzano. Coarse-graining of Volumes for Modeling of Structure and Dynamics in Electron Microscopy: Algorithm to Automatically Control Accuracy of Approximation. IEEE J. Selected Topics in Signal Processing, 10: 161-173 (2016)
106. C. Kervrann, C.O.S. Sorzano, S. Acton, J.C. Olivo-Marin, M. Unser. A guided tour of Selected Image Processing and Analysis Methods for Fluorescence and Electron Microscopy IEEE J. Special Topics in Signal Processing, 10: 6-30 (2016)
107. J. Segura, R. Sanchez-Garcia, D. Tabas-Madrid, J. Cuenca-Alba, C.O.S. Sorzano, J.M. Carazo. 3DIANA: 3D Domain Interaction Analysis. A toolbox for quaternary structure modelling. Biophysical J. 110: 766-775 (2016)
108. A. Iriarte, R.M. Lewitt, R. Marabini, S. Matej, C.O.S. Sorzano. System Models for PET Statistical Iterative Reconstruction: a review. Computerized Medical Imaging and Graphics, 48: 30-48 (2016)
     
109. J. Vargas, J. Oton, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Particle alignment reliability in single particle electron cryomicroscopy: a general approach. Scientific Reports 6: 21626 (2016)
110. D. Tabas-Madrid, J. Segura, R. Sanchez-Garcia, J. Cuenca-Alba, C.O.S. Sorzano, J.M. Carazo. 3DBioNotes: A unified, enriched and interactive view of macromolecular information. J. Structural Biology 194: 231-234 (2016)
     
111. M. Chiappi, J.J. Conesa, E. Pereiro, C.O.S. Sorzano, M.J. Rodriguez, K. Hentzle, G. Schneider, F.J. Chichon, J.L. Carrascosa. Cryo-soft X-ray tomography as a quantitative three-dimensional tool to model nanoparticle:cell interaction. J. Nanobiotechnology 14: 15 (2016)
     
112. C.O.S. Sorzano, A.L. Alvarez-Cabrera, M. Kazemi, J.M. Carazo, S. Jonic. StructMap: Elastic distance analysis of electron microscopy maps for studying conformational changes. Biophysical J. 110: 1753-1765 (2016)
113. C.O.S. Sorzano, A. Martin-Ramos, F. Prieto, R. Melero, J. Martin-Benito, S. Jonic, J. Navas-Calvente, J. Vargas, J. Oton, V. Abrishami, J.M. de la Rosa-Trevin, J. Gomez-Blanco, J.L. Vilas, R. Marabini, J.M. Carazo. Local analysis of strains and rotations for macromolecular electron microscopy maps. J. Structural Biology, 195: 123-128 (2016)
114. S. Jonic, J. Vargas, R. Melero, J. Gomez-Blanco, J.M.Carazo, C.O.S. Sorzano. Denoising of high-resolution single-particle electron-microscopy density maps by their approximation using three-dimensional Gaussian functions. J. Structural Biology 194: 423-433 (2016)
     
115. L. Sanchez-Sampedro, E. Mejias-Perez, C.O.S. Sorzano, J.L. Najera, M. Esteban. NYVAC vector modified by C7L viral gene insertion improves T cell immune responses and effectiveness against leishmaniasis. Virus Research, 220: 1-16 (2016)
116. J.M. de la Rosa-Trevin, A. Quintana, L. del Cano, A. Zaldivar-Peraza, I. Foche, J. Gutierrez, J. Gomez-Blanco, J. Burguet-Castells, J. Cuenca-Alba, V. Abrishami, J. Vargas, J. Oton, G. Sharov, J.L. Vilas, J. Navas, P. Conesa, M. Kazemi, R. Marabini, C.O.S. Sorzano, J.M. Carazo. Scipion: a software framework toward integration, reproducibility, and validation in 3D Electron Microscopy. J. Structural Biology, 195: 93-99 (2016)
     
117. G. Ramirez-Santiago, J. Robles-Valero, G. Morlino, A. Cruz-Adalia, M. Perez-Martinez, A. Zaldivar, M. Torres-Torresano, F.J. Chichon, A. Sorrentino, E. Pereiro, J.L. Carrascosa, D. Megias, C.O.S. Sorzano, F. Sanchez-Madrid, E. Veiga. Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge. European J. of Immunology 46, 2376-2387 (2016)
     
118. J. Vargas, E. Franken, J. Gomez-Blanco, R. Schoenmakers, A. J. Koster, C.O.S. Sorzano, J.M. Carazo. Foil-hole and data image quality assessment in 3DEM: Towards high-throughput image acquisition in the electron microscope. J. Structural Biology 196: 515-524 (2016)
     
119. J.L. Vilas, J. Navas, J. Gomez-Blanco, J.M. de la Rosa-Trevin, R. Melero, I. Peschiera, I. Ferlenghi, J. Cuenca, J.M. Carazo, J.Vargas, C.O.S. Sorzano. Fast and automatic identification of particle tilt pairs based on Delaunay triangulation. J. Structural Biology 196: 525-533 (2016)
120. J. Oton, E. Pereiro, A.J. Perez-Berna, L. Millach, C.O.S. Sorzano, R. Marabini, J.M. Carazo. Characterization of transfer function, resolution and depth of field of a soft X-ray microscope applied to tomography enhancement by Wiener deconvolution. Biomedical Optics Express, 7:5092-5103 (2016)
121. S. Jonic, C.O.S. Sorzano. Versatility of approximating single-particle electron-microscopy density maps using pseudoatoms and approximation-accuracy control. BioMed Research Intl. Article ID 7060348 (2016)
122. C.O.S. Sorzano, J. Vargas, J. Oton, V. Abrishami, J.M. de la Rosa-Trevin, J. Gomez-Blanco, J.L. Vilas, R. Marabini, J.M. Carazo. A review of resolution measures and related aspects in 3D Electron Microscopy. Progress in Biophysics and Molecular Biology 124: 1-30 (2017)
123. A. Vijayan, E. Mejias-Perez, D.A. Espinosa, S.C. Raman, C.O.S. Sorzano, F. Zavala, M. Esteban. A prime/boost PfCS14KM/MVA-sPfCSM vaccination protocol generates robust CD8+ T cell and antibody responses to Plasmodium falciparum circumsporozoite protein and protects mice against malaria. Clinical and Vaccine Immunology, 24:e00494-16 (2017)
124. J. Oton, E. Pereiro, J.J. Conesa, F.J. Chichon, D. Luque, J.M. Rodriguez, A.J. Perez-Berna, C.O.S. Sorzano, J. Klukowska, G.T. Herman, J. Vargas, R. Marabini, J.L. Carrascosa, J.M. Carazo. XTEND: Extending the depth of field in soft X-ray tomography. Scientific Reports, 7: 45808 (2017)
125. A.L. Alvarez-Cabrera, S. Delgado Bermudez, D. Gil Carton, G.B. Mortuza, G. Montoya, C.O.S. Sorzano, T.K. Tang, J.M. Carazo. Structural insights into CPAP oligomeric behavior: The possible hierarchical building of a scaffold. Frontiers in Molecular Biosciences, 4:17 (2017)
126. C.O.S. Sorzano, J. Vargas, J. Oton, J.L. Vilas, M. Kazemi, R. Melero, L. del Caño, J. Cuenca, P. Conesa, J. Gomez-Blanco, R. Marabini, J.M. Carazo. A survey of the use of iterative reconstruction algorithms in Electron Microscopy. BioMed Research Intl. 6482567 (2017)
127. M. Di Pilato, E. Mejias-Perez, C.O.S. Sorzano, M. Esteban. Distinct roles of Vaccinia virus NF-kB inhibitor proteins A52, B15 and K7 in the immune response. J. Virology 91: e00575-17 (2017)
128. M. Martinez, C.O.S. Sorzano, A. Pascual-Montano, J.M. Carazo. Gene signature asociated with benign neurofibroma transformation to malignant peripheral nerve sheath tumors. PLOS One 12: e0178316 (2017)
129. J. Vargas, R. Melero, J. Gomez-Blanco, J.M. Carazo, C.O.S. Sorzano. Quantitative analysis of 3D alignment quality: its impact on soft-validation, particle pruning and homogeneity analysis. Scientific Reports, 7: 6307 (2017)
130. V. Hamel, E. Steib, R. Hamelin, F. Armand, S. Borgers, I. Fluckiger, C. Busso, N. Olieric, C.O.S. Sorzano, M. Steinmetz, P. Guichard, P. Gonczy. Identification of Chlamydomonas central core centriolar proteins reveals a role for human WDR90 in ciliogenesis. Current Biology, 27: 2486-2598.e6 (2017)
131. J. Cuenca, L. del Cano, P. Conesa, J. Gomez-Blanco, J.M. de la Rosa-Trevin, R. Marabini, C.O.S. Sorzano, J.M. Carazo. ScipionCloud: An integrative and interactive gateway for large scale cryo electron microscopy image processing on commercial and academic clouds. J. Structural Biology, 200: 20-27 (2017)
132. J. Segura, R. Sanchez-Garcia, M. Martinez, J. Cuenca-Alba, D. Tabas-Madrid, C.O.S. Sorzano, J.M. Carazo. 3DBioNotes v2.0: A web server for the automatic annotation of macromolecular structures. Bioinformatics, 33:3655-3657 (2017)
133. P Albanese, R. Melero, B.D. Engel, P. Berto, M. Manfredi, A. Chiodoni, J. Vargas, C.O.S. Sorzano, E. Marengo, G. Saracco, G. Zanotti, J.M. Carazo, C. Pagliano. Cryo-EM structure of plant PSII-LHCII supercomplexes physically connected on the stromal side. Scientific Reports, 7: 10067 (2017)
134. Vitalle, J., Zenarruzabeitia, O., Terren, I., Plana, M., Guardo, A.C., Leal, L., Peña, J., Garcia, F., Borrego, F., Mothe, B., Cobarsi, P., Rosas, M., Carmen Puertas, M., Carrillo, J., Blanco, J., Martinez-Picado, J., Clotet, B., Brander, C., Climent, N., Alvarez, C., Sanchez, S., Leon, A., Pich, J., Arnaiz, J.A., Torres, B., Lucero, C., Gatell, J.M., Muñoz-Fernandez, M.A., de Quiros, J.C.L.B., Jimenez, J.L., Esteban, M., Gomez, C.E., Perdiguero, B., Garcia-Arriaza, J., Cepeda, V., C.O.S. Sorzano, Gonzalez, N., Alcami, J., Jimenez, L., Benito, J.M., Rallon, N. Monocytes phenotype and cytokine production in human immunodeficiency virus-1 infected patients receiving a modified vaccinia ankara-based HIV-1 vaccine: Relationship to CD300 molecules expression. Frontiers in Immunology, 8:836 (2017)
135. A.C. Guardo, C.E. Gomez, V. Diaz-Brito, J. Pich, J.A. Arnaiz, B. Perdiguero, J. Garcia-Arriaza, C.O.S. Sorzano, J.L. Jimenez, M.A. Muñoz-Fernandez, J.M. Gatell, M. Esteban, J.C. Lopez Bernaldo de Quiros, F. Garcia, M. Plana. Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization. PLOS One, 12 (10): e0186602 (2017)
136. R. Sanchez-Garcia, C.O.S. Sorzano, J.M. Carazo, J. Segura. 3DCONS-DB: A database of structural position specific scoring matrices. Molecules, 22: 2230 (2017)
137. P. Conesa-Mingo, J. Gutierrez, A. Quintana, J.M. de la Rosa-Trevin, A. Zaldivar-Peraza, J. Cuenca Alba, M. Khazemi, J. Vargas, L. del Caño, J. Segura, C.O.S. Sorzano, J.M. Carazo. Scipion web tools: Easy to use Cryo-EM image processing over the web. Protein Science, 27:269-275 (2018)
138. J.L. Vilas, J. Gomez-Blanco, P. Conesa, R. Melero, J.M. de la Rosa-Trevin, J. Oton, J. Cuenca, R. Marabini, J.M. Carazo, J. Vargas, C.O.S. Sorzano. MonoRes: Automatic and unbiased estimation of local resolution for electron microscopy maps. Structure 26: 337-344 (2018) (Comment at Nature Meth.)
139. C.O.S. Sorzano, E. Fernandez-Gimenez, V. Peredo-Robinson, J. Vargas, T. Majtner, G. Caffarena, J. Oton, J.L. Vilas, J.M. de la Rosa-Trevin, R. Melero, J. Gomez-Blanco, J. Cuenca-Alba, L. del Cano, P.Conesa, R. Marabini, J.M. Carazo. Blind estimation of DED camera gain in Electron Microscopy. J. Structural Biology, 203: 90-93 (2018)
140. D. Fortun, P. Guichard, V. Hamel, C.O.S. Sorzano, N. Banterle, P. Gonczy, M. Unser. Reconstruction from Multiple Particles for 3D Isotropic Resolution in Fluorescence Microscopy. IEEE Trans. Medical Imaging, 37: 1235-1246 (2018)
141. C.E. Gomez, B. Perdiguero, C. Sanchez-Corzo, C.O.S. Sorzano, M. Esteban. Immune modulation of NYVAC-based HIV vaccines by combined deletion of viral genes that act on several signalling pathways. Viruses, 10: 7 (2018)
142. L. Martinez-Muñoz, J.M. Rodriguez-Frade, R. Barroso, C.O.S. Sorzano, J.A. Torreño-Piña, C.A. Santiago, C. Manzo, P. Lucas, L. Barrio, J. Vargas, G. Cascio, Y.R. Carrasco, F. Sanchez-Madrid, M.F. Garcia-Parajo, M. Mellado. CXCR4 transmembrane region VI governs its actin-dependent dynamic clustering, signaling and cell response . Molecular Cell 70: 106-119 (2018)
143. C.O.S. Sorzano, J. Vargas, J.L. Vilas, A. Jimenez-Moreno, J. Mota, T. Majtner, D. Maluenda, M. Martinez, R. Sanchez-Garcia, J. Segura, J. Oton, R. Melero, L. del Cano, P. Conesa, J. Gomez-Blanco, Y. Rancel, R. Marabini, J.M. Carazo. Swarm optimization as a consensus technique for Electron Microscopy Initial Volume. Applied Analysis and Optimization, 2: 299-313 (2018)
144. C.O.S. Sorzano, J. Vargas, J.M. de la Rosa-Trevin, A. Jimenez-Moreno, R. Melero, M. Martinez, E. Ramirez-Aportela, P. Conesa, J.L. Vilas, R. Marabini, J.M. Carazo. A new algorithm for high-resolution reconstruction of Single Particles by Electron Microscopy. J. Structural Biology, 204: 329-337 (2018)
145. M.Q. Marin, P. Perez, C.E. Gomez, C.O.S. Sorzano, M. Esteban, J. Garcia-Arriaza. Removal of the C6 vaccinia virus interferon-Gamma inhibitor in the hepatitis C vaccine candidate MVA-HCV elicited in mice high immunogenicity in spite of reduced host gene expression. Viruses, 10: 414 (2018)
146. B. Perdiguero, S.C. Raman, C. Sanchez, C.O.S. Sorzano, J.R. Valverde, M. Esteban, C. Gomez. Potent HIV-1-specific CD8 T Cell Responses Induced in Mice after Priming with a Multiepitopic DNA-TMEP and Boosting with the HIV vaccine MVA-B. Viruses, 10: 424 (2018)
147. J.B. Heymann, R. Marabini, M. Kazemi, C.O.S. Sorzano, M. Holmdahl, J.H. Mendez, S.M. Stagg, S. Jonic, E. Palovcak, J.P. Armache, J. Zhao, Y. Cheng, G. Pintillie, W. Chiu, A. Patwardhan, J.M. Carazo. The First Single Particle Analysis Map Challenge A Summary of the Assessments. J. Structural Biology, 204: 291-300 (2018)
148. S.T.N. Silva, J. Brito, R. Arranz, C.O.S. Sorzano, C. Ebel, J. Doutch, M. Tully, J.M. Carazo, J.L. Carrascosa, P.M. Matias, T.M. Bandeiras. Structure of human RuvB-Like 2 provides mechanism for coupling between ATP binding and mechanical action. Scientific reports: 13726 (2018)
149. R. Sanchez-Garcia, J. Segura, D. Maluenda, J.M. Carazo, C.O.S. Sorzano. Deep Consensus, a deep learning-based approach for the particle pruning in cryo electron microscopy. IUCR Journal 5(Pt 6):854-865 (2018)
150. L. Donati, M. Nilchian, C.O.S. Sorzano, M. Unser. Fast multiscale reconstruction for Cryo-EM. J. Structural Biology, 204: 543-554 (2018)
151. R. Marabini, M. Kazhemi, C.O.S. Sorzano, J.M. Carazo. Map Challenge: Analysis using Pair Comparison Method. J. Structural Biology, 254: 527-542 (2018)
152. J. Gomez-Blanco, J.M. de la Rosa-Trevin, R. Marabini, L. del Cano, A. Jimenez, M. Martinez, R. Melero, T. Majtner, D. Maluenda, J. Mota, Y. Rancel, E Ramirez-Aportela, J.L. Vilas, M. Carroni, S. Fleischmann, E. Lindahl, A.W. Ashton, M. Basham, D.K. Clare, K. Savage, C.A. Siebert, G.G. Sharov, C.O.S. Sorzano, P. Conesa, J.M. Carazo. Using Scipion for Stream Image Processing at Cryo-EM Facilities. J. Structural Biology, 204: 457-463 (2018)
153. J.L. Vilas, N. Tabassum, J. Mota, D. Maluenda, A. Jimenez, T. Majtner, J.M. Carazo, S. Acton, C.O.S. Sorzano. Latest advances in image processing for single particle analysis by cryo-electron microscopy and challenges ahead. Current Opinion in Structural Biology, 52: 127-145 (2018)
154. P. Perez, M.Q. Marin, A. Lazaro-Frias, N. Jimenez de Oya, A.B. Blazquez, E. Escribano-Romero, C.O.S. Sorzano, J. Ortego, J.C. Saiz, M. Esteban, M.A. Martin-Acebes, J. Garcia-Arriaza. A Vaccine Based on a Modified Vaccinia Virus Ankara Vector Expressing Zika Virus Structural Proteins Controls Zika Virus Replication in Mice. Scientific Reports 8: 17385 (2018)
155. C.O.S. Sorzano, A. Jimenez, J. Mota, J.L. Vilas, D. Maluenda, M. Martinez, E. Ramirez-Aportela, T. Majtner, J. Segura, R. Sanchez-Garcia, Y. Rancel, L. del Caño, P. Conesa, S. Jonic, J. Vargas, F. Cazals, Z. Freyberg, J. Krieger, I. Bahar, R. Marabini, J.M. Carazo. Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy. Acta Crystallographica Section F 75: 19-32 (2019)
156. R. Sanchez-Garcia, C.O.S. Sorzano, J.M. Carazo, J. Segura. BIPSPI: xgBoost based interface prediction for partner-specific protein interactions. Bioinformatics 35: 470-477 (2019)
157. D. Strelak, C.O.S. Sorzano, J.M. Carazo, J. Filipovic. A GPU Acceleration of 3D Fourier Reconstruction in Cryo-EM. Intl. J. High-Performance Computing Applications, 1094342019832958 (2019)
158. A. Jimenez-Moreno, S. Jonic, J. Oton, J.L. Vilas, D. Maluenda, J. Mota, M. Martinez, Y. Rancel, J. Segura, R. Sanchez-Garcia, R. Melero, J. Gomez-Blanco, L. del Cano, P. Conesa, L. Skjaerven, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Validation of EM initial models via SAXS curves. Bioinformatics 35: 2427-2433 (2019)
159. M.Q. Marin, P. Perez, K. Ljungberg, C.O.S. Sorzano, C.E. Gomez, P. Liljestrom, M. Esteban, J. Garcia-Arriaza. Potent Anti-Hepatitis C Immune Responses Induced in Mice Vaccinated with DNA-launched RNA Replicons and MVA-HCV. J. Virology, 93: e00055-19 (2019)
160. C.O.S. Sorzano, L. Martinez-Muñoz, G. Cascio, J. Vargas, J.M. Rodriguez-Frade, M. Mellado. Image Processing Protocol for the Analysis of the diffusion of isolated particles by fluorescence microscopy. J. Visualized Experiments, 146: e59314 (2019) (Video)
161. B. Perdiguero, C. Sanchez-Corzo, C.O.S. Sorzano, L. Saiz, P. Mediavilla, M. Esteban, C.E. Gomez. A novel MVA-based HIV vaccine candidate (MVA-gp145-GPN) co-expressing clade C membrane-bound trimeric gp145 Env and Gag-induced virus-like particles (VLPs) triggered broad and multifunctional HIV-1-specific T cell and antibody responses. Viruses 11, 2: 160 (2019)
162. J. Segura, R. Sanchez-Garcia, C.O.S. Sorzano, J.M. Carazo. 3DBIONOTES v3.0: Crossing molecular and structural biology data with genomic variations. Bioinformatics 35: 3512-3513 (2019)
163. I. Peschiera, M. Giuliani, F. Giusti, R. Melero, E. Paccagnini, D. Donnarumma, W. Pansegrau, J.M. Carazo, C.O.S. Sorzano, M. Scarselli, V. Masignani, L.J. Liljeroos, I. Ferlenghi Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H binding protein. Communications Biology 2: 241 (2019)
164. B. Perdiguero, C. Sánchez-Corzo, C.O.S. Sorzano, P. Mediavilla, L. Saiz, M. Esteban, C.E. Gómez. Induction of broad and polyfunctional HIV-1-specific T cell responses by the multiepitopic protein TMEP-B vectored by MVA virus. Vaccines 7, 57 (2019)
165. E. Ramírez-Aportela, J. Mota, P. Conesa, J.M. Carazo, C.O.S. Sorzano. DeepRes: A New Deep Learning and aspect-based Local Resolution Method for Electron Microscopy Maps . IUCR J 6: 1054-1063 (2019)
166. D. Maluenda, T. Majtner, P. Horvarth, J.L. Vilas, A. Jimenez-Moreno, J. Mota, E. Ramirez-Aportela, R. Sanchez-Garcia, P. Conesa, L. del Caño, Y. Rancel, Y. Fonseca, M. Martinez, G. Sharov, C.A. Garcia, D. Strelak, R. Melero, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Flexible workflows for on-the-fly electron microscopy single particle image processing using Scipion. Acta Cryst D 75: 882-894 (2019)
167. P. Brown, RELISH consortium, Y. Zhou. Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database 2019:baz085 (2019)
168. S.C. Raman, E. Mejías-Pérez, C.E. Gomez, J. Garcia-Arriaza, B. Perdiguero, A. Vijayan, M.M. Perez, A. Cuervo, C. Santiago, C.O.S. Sorzano, C. Sánchez-Corzo, M. Stadnik-Spiewak, C. Moog, J.A. Burger, A. Schorcht, R.W. Sanders, J.L. Carrascosa, M. Esteban. The envelope-based fusion antigen GP120C14K forming hexamer-like structures triggers T cell and neutralizing antibody responses against HIV-1. Frontiers Immunology 10: 2793 (2019)
169. P. Pérez, M.Q. Marín, A. Lázaro-Frías, C.O.S. Sorzano, M. Di Pilato, C.E. Gómez, M. Esteban, J.F. Garcia-Arriaza. An MVA Vector Expressing HIV-1 Envelope Under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design. Vaccines 7: 208 (2019)
170. B. Perdiguero, C.E. Gómez, J. García-Arriaza, C. Sánchez-Corzo, C.O.S. Sorzano, S. Wilmschen, D. Von Laer, B. Asbach, C. Schmalzl, D. Peterhoff, S. Ding, R. Wagner, J. Kimpel, Y. Levy, G. Pantaleo, M. Esteban. Heterologous Combination of VSV-GP and NYVAC Vectors Expressing HIV-1 Trimeric gp145 Env as Vaccination Strategy to Elicit Balanced T and B Cell Immune Responses. Frontiers Immunology 10: 2941 (2019)
171. S. Jonic, C.O.S. Sorzano, M. Harastani. Hybrid Electron Microscopy Normal Mode Analysis (HEMNMA) with Scipion. Protein Science 29: 223-236 (2020)
172. J.L. Vilas, J. Otón, C. Messaoudi, R. Melero, P. Conesa, E. Ramirez-Aportela, J. Mota, M. Martínez, A. Jimenez-Moreno, R. Marabini, C.O.S. Sorzano, J. Vargas, J.M. Carazo. Measurement of local resolution in electron tomography. J. Structural Biology X, 4: 100016 (2020)
173. J.L. Vilas, H.D. Tagare, J. Vargas, J.M. Carazo, C.O.S. Sorzano. Measuring local-directional resolution and local anisotropy in cryoEM maps. Nature Communications 11: 55 (2020)
174. E. Ramirez-Aportela, J.L.Vilas, A. Glukhova, R. Melero, P. Conesa, M. Martinez, D. Maluenda, J. Mota, A. Jimenez, J. Vargas, R. Marabini, P.M. Sexton, J.M. Carazo, C.O.S. Sorzano. Automatic local resolution-based sharpening of cryo-EM maps. Bioinformatics 36: 765-772 (2020)
175. J.L. Vilas, J. Vargas, M. Martínez, E. Ramírez-Aportela, R. Melero, A. Jiménez-Moreno, E. Garduño, P. Conesa, R. Marabini, D. Maluenda, J.M. Carazo, C.O.S. Sorzano. Re-examining the spectra of macromolecules. Current practice of spectral quasi B-factor flattening. J. Structural Biology 209: 107447 (2020)
176. M. Martínez, A. Jiménez-Moreno, D. Maluenda, E. Ramírez-Aportela, R. Melero, A. Cuervo, P. Conesa, L. Del Caño, Y.C. Fonseca, R. Sánchez-García, D. Strelak, J.J. Conesa, E. Fernández-Giménez, F. de Isidro, C.O.S. Sorzano, J.M. Carazo, R. Marabini. Integration of Cryo-EM Model Building Software in Scipion. J. Chemical Information and Modelling 60: 2533-2540 (2020)
177. P. Pérez, M.Q. Marín, A. Lázaro-Frías, C.O.S. Sorzano, C.E. Gómez, M. Esteban, J.F. Garcia-Arriaza. Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B. Vaccines 8: 70 (2020)
178. R. Coloma, R. Arranz, J.M. de la Rosa-Trevin, C.O.S. Sorzano, S. Munier, D. Carlero, N. Naffakh, J. Ortin, J. Martin-Benito. The processive helical track: A structural model for influenza virus transcription and replication. Nature Microbiology 5: 727-734 (2020)
179. M. Iriondo-DeHond, A. Iriondo-DeHond, T. Herrera, A.M. Fernandez-Fernandez, C.O.S. Sorzano, E. Miguel, M.D. del Castillo. Sensory Acceptance, Appetite Control and Gastrointestinal Tolerance of Yogurts Containing Coffee-cascara Extract and Inulin. Nutrients 12: 627 (2020)
180. J.L. Vilas, B. Heymann, H. Tagare, E. Ramirez-Aportela, J.M. Carazo, C.O.S. Sorzano. Local resolution estimates of cryoEM reconstructions. Current Opinion in Structural Biology 64: 74-78 (2020)
181. D. Strelak, J. Filipovic, A. Jiménez-Moreno, J.M. Carazo, C.O.S. Sorzano. FlexAlign: an accurate and fast algorithm for movie alignment in Cryo-Electron Microscopy. Electronics 9, 1040, (2020)
182. R. Sánchez-García, J. Segura, D. Maluenda, C.O.S. Sorzano, J.M. Carazo. MicrographCleaner: a python package for cryo-EM micrograph segmentation using deep learning. J. Structural Biology 210: 107498 (2020)
183. M.Q. Marín, K. Sliepen, J. García-Arriaza, S. Koekkoek, P. Pérez, C.O.S. Sorzano, C.E. Gómez, R.W. Sanders, M. Esteban. Optimized hepatitis C virus (HCV) E2 glycoproteins and their immunogenicity in combination with MVA-HCV. Vaccines 8: 440 (2020)
184. R. Melero, C.O.S. Sorzano, B. Foster, J.L. Vilas, M. Martínez, R. Marabini, E. Ramírez-Aportela, R. Sánchez-García, D. Herreros, L. del Caño, P. Losana, Y. Fonseca-Reyna, P. Conesa, D. Wrapp, P. Chacón, J.S. McLellan, H.D. Tagare, J.M. Carazo. Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures. IUCR J 7: 1059-1069 (2020) Video
185. C.O.S. Sorzano, F. de Isidro-Gómez, E. Fernández-Giménez, D. Herreros, S. Marco, J.M. Carazo, C. Messaoudi. Improvements on marker-free images alignment for electron tomography. J. Structural Biology X, 4: 137 (2020)
186. Y. Zhang, J. Krieger, K. Mikulska-Ruminska, B. Kaynak, C.O.S. Sorzano, J.M. Carazo, J. Xing, I. Bahar. State-Dependent Sequential Allostery Exhibited by Chaperonin TRiC/CCT Revealed by Network Analysis of Cryo-EM Maps. Progress in Biophysics and Molecular Biology 160: 104-120 (2021)
187. A. Jiménez, D. Strelak, J. Filipovic, J.M. Carazo, C.O.S. Sorzano. DeepAlign, a 3D alignment method based on regionalized deep learning. J. Structural Biology 213: 107712 (2021)
188. C.O.S. Sorzano, M.A. Perez de la Cruz-Moreno, F.R. Martin, C. Montejo, A. Aguilar-Ros. A signal processing approach to pharmacokinetic data analysis. Pharmaceutical Research, 38: 625–635 (2021)
     
189. E. Ramírez-Aportela, D. Maluenda, Y.C. Fonseca, P. Conesa, R. Marabini, B. Heymann, J.M. Carazo, C.O.S. Sorzano. FSC-Q: A CryoEM map-to-atomic model quality validation based on the local Fourier Shell Correlation. Nature Communications 12: 42 (2021)
190. C.O.S. Sorzano, D. Semchonok, S.C. Lin, J.L. Vilas, A. Jimenez-Moreno, M. Gragera, D. Maluenda, M. Martinez, E. Ramirez-Aportela, R. Melero, A. Cuervo, P. Conesa, L. del Caño, Y.C. Fonseca, R. Sánchez-García, D. Strelak, E. Fernández-Giménez, F. de Isidro, P. Kastritis, R. Marabini, B. Bruce, J.M. Carazo. Algorithmic robustness to preferred orientations in Single Particle Analysis by CryoEM. J. Structural Biology 213: 107695 (2021)
191. J. García-Arriaza, U. Garaigorta, P. Pérez, A. Lázaro-Frías, C. Zamora, P. Gastaminza, C. del Fresno, J.M. Casasnovas, C.O.S. Sorzano, D. Sancho, M. Esteban. COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike induce robust T- and B-cell immune responses and full efficacy in mice. J. Virology 95: e02260-20 (2021) (JVI spotlight)
192. M. Kazhemi, C.O.S. Sorzano, A. des Georges, R. Efremov, J.M. Carazo, J. Vargas. ENRICH: a method to improve the quality of heterogeneous macromolecular reconstructions. Progress in Biophysics and Molecular Biology, 164: 92-100 (2021)
193. C.E. Gómez, B. Perdiguero, M. Falqui, M.Q. Marín, M. Bécares, C.O.S. Sorzano, J. García-Arriaza, M. Esteban, S. Guerra. Enhancement of HIV-1 Env-specific CD8 T cell responses using IFN-Stimulated Gene 15 (ISG15) as an immune adjuvant. J. Virology 95, e01155-20 (2021)
194. A. Jiménez-Moreno, L. del Caño, M. Martínez, E. Ramírez-Aportela, A. Cuervo, R. Melero, R. Sánchez-García, D. Strelak, E. Fernández-Giménez, F. de Isidro-Gómez, D. Herreros, P. Conesa, Y. Fonseca, D. Maluenda, J. Jiménez de la Morena, J.R. Macías, P. Losana, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Cryo-EM and Single-Particle Analysis with Scipion. J. of Visualized Experiments, 171: e62261 (2021) (Video)
195. M. Di Pilato, M. Palomino-Segura, E. Mejías-Pérez, R. D'Antuono, D.U. Pizzagalli, P. Pérez, C.O.S. Sorzano, S.F. González, M. Esteban. Neutrophil Subtypes Shape HIV-specific CD8 T Cell Responses After Vaccinia Virus Infection. NPJ Vaccines, 6: 52 (2021)
196. C.O.S. Sorzano, J.M. Carazo. PCA is limited to low resolution analysis in CryoEM. Acta Crystallographica Section D, D77: 835-839 (2021)
197. C. Wert Carvajal, R. Sánchez-García, J.R. Macías, R. Sanz-Pamplona, A. Méndez Pérez, R. Alemany, E. Veiga, C.O.S. Sorzano, A. Muñoz-Barrutia. Predicting MHC I restricted T cell epitopes in mice with NAP-CNB, a novel online tool. Scientific Reports, 11: 10780 (2021)
198. J.R. Macías, R. Sánchez-García, P. Conesa, E. Ramírez-Aportela, M. Martínez, C. Wert Carvajal, J. Segura, S. Horrell, A. Thorn, C.O.S. Sorzano, J.M. Carazo. 3DBionotes COVID-19 Edition. Bioinformatics, 37: 4258-4260 (2021)
199. C.O.S. Sorzano, Y. Fonseca, M.A. Pérez de la Cruz Moreno. Scipion PKPD: an open-source platform for Biopharmaceutics, Pharmacokinetics and Pharmacodynamics Data Analysis. Pharmaceutical Research, 38: 1169-1178 (2021)
200. R. Sánchez-García, J. Gómez-Blanco, A. Cuervo, J.M. Carazo, C.O.S. Sorzano, J. Vargas. DeepEMhancer: a deep learning solution for cryo-EM volume post-processing. Communications Biology, 4: 874 (2021)
201. P. Pérez, M.A. Martín-Acebes, T. Poderoso, A. Lázaro-Frías, J.C. Saiz, C.O.S. Sorzano, M. Esteban, J.F. García-Arriaza. The combined vaccination protocol of DNA/MVA expressing Zika virus structural proteins as efficient inducer of T and B cell immune responses. Emerging Microbes & Infections, 10(2021)
202. J. Méndez, E. Garduño, J.M. Carazo, C.O.S. Sorzano. Identification of incorrectly oriented particles in CryoEM Single Particle Analysis. J. Structural Biology, 213: 107771 (2021)
203. E. Fernández-Giménez, M. Martínez, R. Sánchez-García, R. Marabini, E. Ramírez-Aportela, P. Conesa, J.M. Carazo, C.O.S. Sorzano. Cryo-EM density maps adjustment for subtraction, consensus and sharpening. J. Structural Biology, 213: 107780 (2021)
204. S. Sorrentino, J. Conesa, A. Cuervo, R. Melero, B. Martins, M.E. Fernández-Giménez, F. de Isidro, J. Jiménez, J.D. Studt, C.O.S. Sorzano, M. Eibauer, J.M. Carazo, O. Medalia. Structural analysis of receptors and actin polarity in platelet protrusions. PNAS 118: e2105004118 (2021)
205. D. Herreros, R.R. Lederman, J. Krieger, A. Jiménez-Moreno, M. Martínez, I. Bahar, J.M. Carazo, C.O.S. Sorzano. Approximating deformation fields for the analysis of continuous heterogeneity of biological macromolecules by 3D Zernike polynomials. IUCR J, 8: eh5012 (2021)
206. C.E. Gómez, B. Perdiguero, L. Usero, L. Marcos-Villar, L. Miralles, L. Leal, C.O.S. Sorzano, C. Sánchez-Corzo, M. Plana, F. García, M. Esteban. Enhancement of the HIV-1-specific immune response induced by an mRNA vaccine through boosting with a poxvirus MVA vector expressing the same antigen. Vaccines 9, 959 (2021)
207. D. Strelak, A. Jiménez-Moreno, J.L. Vilas, E. Ramírez-Aportela, R. Sánchez-García, D. Maluenda, J. Vargas, D. Herreros, E. Fernández-Giménez, F. de Isidro-Gómez, J. Horacek, D. Myska, M. Horacek, P. Conesa, Y.C. Fonseca-Reyna, J. Jiménez, M. Martínez, M. Harastani, S. Jonic, J. Filipovic, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Advances in Xmipp for Cryo-electron Microscopy: From Xmipp to Scipion. Molecules, 26: 6224 (2021)
208. D.A. Semchonok, J. Mondal, S.J. Cooper, K. Schlum, M. Li, M. Amin, C.O.S. Sorzano, E. Ramírez-Aportela, P. Kastritis, E.J. Boekema, A. Guskov, B.D. Bruce. Cryo-EM Structure of a Tetrameric Photosystem I from Chroococcidiopsis TS-821, a Thermophilic, unicellular, Non-heterocyst-forming Cyanobacteria. Plant communications, 2: 100248 (2021)
209. C.O.S. Sorzano, A. Jimenez-Moreno, D. Maluenda, M. Martinez, E. Ramirez-Aportela, R. Melero, A. Cuervo, J. Conesa, J. Filipovic, P.Conesa, L. del Caño, Y.C. Fonseca, J. Jiménez-de la Morena, P. Losana, R. Sáchez-García, D. Strelak, E. Fernandez-Gimenez, F. de Isidro, D.Herreros, J.L. Vilas, R. Marabini, J.M. Carazo. On bias, variance, overfitting, gold standard and consensus in Single Particle Analysis by Cryo-electron microscopy. Acta Crystallographica Section D, D78: 410-423 (2022)
210. M. Varadi, S. Anyango, D. Armstrong, J. Berrisford, P. Choudhary, M. Deshpande, N. Nadzirin, S.S. Nair, L. Pravda, A. Tanweer, B. Al-Lazikani, C. Andreini, G.J. Barton, D. Bednar, K. Berka, T. Blundell, K.P. Brock, J.M. Carazo, J. Damborsky, A. David, S. Dey, R. Dunbrack, J. Fernandez Recio, F. Fraternali, T. Gibson, M. Helmer-Citterich, D. Hoksza, T. Hopf, D. Jakubec, N. Kannan, R. Krivak, M. Kumar, E. D Levy, N. London, J.R. Macias, M.M. Srivatsan, D.S. Marks, L. Martens, S.A. McGowan, J.E. McGreig, V. Modi, R. Gonzalo Parra, G. Pepe, D. Piovesan, J. Prilusky, V. Putignano, L.G. Radusky, P. Ramasamy, A. O Rausch, N. Reuter, L.A. Rodriguez, N.J. Rollins, A. Rosato, P. Rubach, L. Serrano, G. Singh, P. Skoda, C.O.S. Sorzano, J. Stourac, J.I. Sulkowska, R. Svobodova, N. Tichshenko, S.C.E. Tosatto, W. Vranken, M.N. Wass, D. Xue, D. Zaidman, J. Thornton, M. Sternberg, C. Orengo, S. Velankar PDBe-KB: collaboratively defining the biological context of structural data. Nucleic Acids Research, 50: gkab988 (2022)
211. M.A. Cuesta-Geijo, I.García-Dorival, A. del Puerto, J. Urquiza, I. Galindo, F. Lasala, A. Cayuela, L. Barrado-Gil, C.O.S. Sorzano, C. Gil, R. Delgado, C. Alonso. New insights into the role of endosomal proteins for African swine fever virus infection. PLOS Pathogens, 18: e1009784 (2022)
212. J. Krieger, C.O.S. Sorzano, J.M. Carazo, I. Bahar. Protein Dynamics Developments for Large Scale and CryoEM: Case Study of ProDy 2.0. Acta Crystallographica Section D, D78: S2059798322001966 (2022)
213. J.L. Vilas, J.M. Carazo, C.O.S. Sorzano. Emerging themes in cryoEM-SPA Image processing. Chemical reviews, 122: 13915-13951 (2022)
214. R. Sánchez-García, J.R. Macías, C.O.S. Sorzano, J.M. Carazo, J. Segura. BIPSPI+: Mining type-specific datasets of protein complexes to improve protein binding site prediction. J. Molecular Biology, 434: 167556 (2022)
215. C.O.S. Sorzano, J.L. Vilas, E. Ramírez-Aportela, D. del Hoyo, D. Herreros, E. Fernandez-Giménez, D. Marchán, F. de Isidro Gómez, J.R. Macías, I. Sánchez, L. del Caño, Y. Fonseca-Reyna, P. Conesa, A. García-Mena, J. Burguet, J. García Condado, J. Méndez García, M. Martínez, A. Muñoz Barrutia, R. Marabini, J. Vargas, J.M. Carazo. Image processing tools for the validation of CryoEM maps. Faraday Discussions, 240: 210-227 (2022)
216. C.O.S. Sorzano, J.M. Carazo. Cryo-Electron Microscopy: the field of 1,000+ methods. J. Structural Biology, 214: 107861 (2022)
217. J. Jiménez de la Morena, P. Conesa, Y.C. Fonseca, F.P. de Isidro-Gómez, D. Herreros, E. Fernández-Giménez, D. Strelak, E. Moebel, T.O. Buchholz, F. Jug, A. Martinez-Sanchez, J.J. Conesa, A. Cuervo, P. Losana, I. Sánchez, M. Iceta, L. del Cano, M. Gragera, R. Melero, G. Sharov, D. Castaño-Díez, A. Koster, J.G. Piccirillo, J.L. Vilas, J. Otón, R. Marabini, C.O.S. Sorzano, J. M. Carazo. ScipionTomo: towards cryo-electron tomography software integration, reproducibility, and validation. J. Structural Biology, 214: 107872 (2022)
218. A. Cayuela-López, J.A. Gómez-Pedrero, A.M. Oña Blanco, C.O.S. Sorzano. Cell-TypeAnalyzer: A flexible Fiji/ImageJ plugin to classify cells according to user-defined criteria. Biological Imaging, 2: e5 (2022)
219. T. Ginex, M. Wieczór, C.P. Mata, J. Krieger, M.L. López-Redondo, C. Francés-Gómez, P. Ruiz-Rodríguez, R. Melero, C.O.S. Sorzano, M. Martínez, N. Gougeard, A. Forcada-Nadal, S. Zamora-Caballero, R. Gozalbo-Rovira, C. Sanz-Frasquet, J. Bravo, V. Rubio, A. Marina, R. Geller, I. Comas, C. Gil, M. Coscolla, M. Orozco, J.L. Llácer, J.M. Carazo, C. Marco-Marín. The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of S:A222V. PLOS Pathogens, 18: e1010631 (2022)
220. E. Ramírez-Aportela, J.M. Carazo, C.O.S. Sorzano. Higher resolution in CryoEM by the combination of macromolecular prior knowledge and image processing tools. IUCR J, 9: 632-638 (2022)
221. T. Bepler, A.J. Borst, J. Bouvette, G. Cannone, S. Chen, A. Cheng, A. Cheng, Q. Fan, F. Grollios, H. Gupta, M. Gupta, T. Humphreys, P.T. Kim, H. Kuang, Y. Li, A. Noble, A. Punjani, W. Rice, C.O.S. Sorzano, S. Stagg, J. Strauss, L. Yu, B. Carragher, C.S. Potter. Smart Data Collection for CryoEM. J. Structural Biology, 214: 107913 (2022)
222. J. García Condado, A. Muñoz-Barrutia, C.O.S. Sorzano. Automatic determination of the handedness of Single-Particle maps of macromolecules solved by CryoEM. J. Structural Biology, 214: 107915 (2022)
223. C.O.S. Sorzano, M.A. Pérez-de-la-Cruz Moreno, J.L.Vilas. An analytical solution for saturable absorption in pharmacokinetics models. Pharmaceutical Research , s11095-022-03455-z (2023)
224. D. Herreros, R.R. Lederman, J. Krieger, A. Jimenez-Moreno, M. Martinez, D. Myska, D. Strelak, J. Filipovic, I. Bahar, J.M. Carazo, C.O.S. Sorzano. Estimating conformational landscapes from CryoEM particles by 3D Zernike polynomials. Nature Communications, 14: 154 (2023)
225. A. Kulczyk, C.O.S. Sorzano, P. Grela, M. Tchórzewski, N.E. Tumer, X.P. Li. Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction. J. Biological Chemistry, 299: 102795 (2023, cover article)
226. A.G. Vesga, L. Villegas, C. Vequi-Suplicy, C.O.S. Sorzano, J. Requejo-Isidro. Quantitative characterisation of membrane-protein reversible association using FCS. Biophysical J., 122: 1-16 (2023)
227. D. Herreros, J. Kiska, E. Ramírez-Aportela, J. Filipovic, J.M. Carazo, C.O.S. Sorzano. ZART: A novel multiresolution reconstruction algorithm with motion-blur correction for single particle analysis. J. Molecular Biology, 435: 168088 (2023)
228. M. Falqui, B. Perdiguero, R. Coloma, M. Albert, L. Marcos, J. Patrick McGrail, C.O.S. Sorzano, M. Esteban, C.E. Gomez, S. Guerra. An MVA-based vector expressing-free-ISG15 increase IFN-I and improves HIV-1-specific CD8+ T cell immune response. Frontiers in Cellular and Infection Microbiology, 13: 1187193. (2023)
229. D. Herreros, J. Krieger, Y. Fonseca, P. Conesa, M. Harastani, R. Vuillemot, I. Hamitouche, R. Serrano Gutiérrez, M. Gragera, R. Melero, S. Jonic, J.M. Carazo, C.O.S. Sorzano. Scipion Flexibility Hub: An integrative framework for advanced conformational heterogeneity analysis in CryoEM. Acta Crystallographica, D79 (2023)
230. B. Perdiguero, L. Marcos, M. Lopez-Bravo, P.J. Sanchez-Cordon, C. Zamora, J.R. Valverde, C.O.S. Sorzano, L. Sin, E. Álvarez, M. Ramos, M. del Val, M. Esteban, C.E. Gomez. Immunogenicity and efficacy of a novel multi-patch SARS-CoV-2/COVID-19 vaccine candidate. Frontiers in Immunology, 14: 1160065 (2023)
231. A. Cayuela, P. Conesa, A. Oña, J.A. Gómez-Pedrero, C.O.S. Sorzano. Real-Time Correction of Chromatic Aberration in Optical Fluorescence Microscopy. Methods and Applications in Fluorescence, 11: 045001 (2023)
232. B. Soler Palacios, R. Villares, P. Lucas, J.M. Rodríguez-Frade, A. Cayuela, J.G. Piccirillo, D. Delgado Gestoso, C. Risco, C.O.S. Sorzano, N. Martínez, J.J. Conesa, F.J. Iborra, M. Mellado. Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming. Frontiers in Immunology, 14: 1200259 (2023)
233. P. Conesa, A. Cuervo, A. García Mena, D. del Hoyo, D. Herreros, D. Marchan, D. Strelak, E. Fernández-Giménez, E. Ramírez-Aportela, F.P. de Isidro-Gómez, G. Sharov, I. Sánchez, J. Krieger, J. Jiménez de la Morena, J.L. Vilas, J.M. de la Rosa-Trevín, L. del Caño, M. Gragera, M. Iceta, M. Martínez, P. Losana, R. Melero, Y.C. Fonseca, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Scipion3: a workflow engine for cryoelectron microscopy image processing and structural biology. Biological Imaging, 3: e13 (2023)
234. E. Fernández-Giménez, J.M. Carazo, C.O.S. Sorzano. Local defocus estimation in Single Particle Analysis in Cryo-Electron Microscopy. J. Structural Biology, 215: 108030 (2023)
235. E. Fernández-Giménez, M. Martínez, R. Marabini, D. Strelak, R. Sánchez, J.M. Carazo, C.O.S. Sorzano. A new algorithm to eliminate unwanted signals in single particle analysis. J. Structural Biology, 215: 108024 (2023)
236. J. Krieger, C.O.S. Sorzano, J.M. Carazo. Scipion-EM-ProDy: A graphical interface for the ProDy Python package within the Scipion workflow engine enabling integration of databases, simulations and cryo-electron microscopy image processing. Intl. J. Molecular Sciences, 24: 241814245 (2023)
237. D. Strelak, D. Marchán, J.M. Carazo, C.O.S. Sorzano. Performance and quality comparison of movie alignment software for Cryo-EM. Micromachines, 14: 1835 (2023)
238. C.O.S. Sorzano, I. Sánchez, A. Naranjo. Statistical design for health monitoring in laboratory animal facilities using sentinel animals. Laboratory animals (in press)
239. B. Perdiguero, A. Hauser, C.E. Gomez, D. Peterhoff, E. Sideris, C.O.S. Sorzano, S. Wilmschen, M. Schaber, L. Stengel, B. Asbach, S. Ding, D. Von Laer, Y. Levy, G. Pantaleo, J. Kimpel, M. Esteban, R. Wagner. Potency and durability of T and B cell immune responses after homologous and heterologous vector delivery of a trimer-stabilized, membrane-displayed HIV-1 clade ConC Env protein. Frontiers in Immunology, 14: 1270908. (2023)
240. D. del Hoyo, A. Lomas, E. Ulzurrun, N. Campillo, C.O.S. Sorzano. Scipion-chem: an open platform for Virtual Drug Screening. J. Chemical Information and Modelling, 63: 7873-7885 (2023)
241. A. Cayuela, E. García-Cuesta, J.A. Gomez-Pedrero, S.R. Gardeta, J.M. Rodriguez-Frade, M. Mellado, C.O.S. Sorzano. TrackAnalyzer: A Toolbox for a holistic analysis of Single-Particle Tracks. Biological Imaging, 3: e18 (2023)
242. F. de Isidro-Gómez, J.L. Vilas, J.M. Carazo, C.O.S. Sorzano. A deep learning approach to the automatic detection of alignment errors in cryo-electron tomographic reconstructions. J. Structural Biology, 216: 108056 (2024)
243. C.E. Gómez, L. Marcos, B. Perdiguero, S. Anthiya, M. Borrajo, G. Lou, L. Franceschini, I. Esteban, P. Sánchez-Cordón, C. Zamora, C.O.S. Sorzano, L. Jordá, L. Codó, J.L. Gelpí, M. Sisteré-Oró, A. Meyerhans, K. Thielemans, F. Martínez-Jiménez, N. López-Vigas, F. Garcia, M. Alonso, M. Plana, M. Esteban. Modulating the Immune Response to SARS-CoV-2 by Different Nanocarriers Delivering a mRNA Expressing Trimeric RBD of the Spike Protein: COVARNA Consortium. NPJ Vaccines (in press)
244. G.J. Kleywegt, P.D. Adams, S.J. Butcher, C.Lawson, A.Rohou, P.B. Rosenthal, S.Subramaniam, M.Topf, S.Abbott, P.R. Baldwin, J.M. Berrisford, G. Bricogne, P. Choudhary, T.I. Croll, R. Danev, S.J. Ganesan, T. Grant, A. Gutmanas, R. Henderson, J.B. Heymann, J.T. Huiskonen, A. Istrate, T. Kato, G.C. Lander, S.M. Lok, S.J. Ludtke, R. Pye, G.D. Pintilie, J.S. Richardson, C. Sachse, O. Salih, S.H.W. Scheres, C.O.S. Sorzano, S.M. Stagg, Z. Wang, R. Warshamanage, J.D. Westbrook, M.D. Winn, J.Y. Young, S.K. Burley, J.C. Hoch, G. Kurisu, K. Morris, A. Patwardhan, S. Velankar. Community recommendations on cryoEM data archiving and validation. IUCRJ, 11: 1-12 (2024)
245. P. Núñez, J.L. Vilas, J.R. Macías, A. Muñoz-Barrutia, J.M. Carazo, C.O.S. Sorzano. A strong association between α-helices and epitopes. (submitted)
246. Adams, Butcher, Lawson, Rohou, Rosenthal, Subramaniam, Topf, Abbott, Baldwin, Berrisford, Bricogne, Choudhary, Croll, Danev, Ganesan, Grant, Gutmanas, Henderson, Heymann, Huiskonen, Istrate, Kato, Lander, Lok, Ludtke, Mitsuoka, Pie, Pintilie, Richardson, Sachse, Salih, Scheres, C.O.S. Sorzano, Stagg, Wang, Warshamanage, Westbrook, Winn, Young, Burley, Hoch, Kurisu, Patwardhan, Velankar. Community recommendations on cryo-EM data archiving and validation. (submitted)
247. A. Méndez-Pérez, A.M. Acosta-Moreno, C. Wert-Carvajal, P. Ballesteros-Cuartero, R. Sánchez-García, J.R. Macías, R. Sanz-Pamplona, R. Alemany, C.O.S. Sorzano, A. Muñoz-Barrutia, E. Veiga. Unraveling the Power of NAP-CNB's Machine Learning-enhanced Tumor Neoantigen Prediction. (submitted)
248. S. Vacca, M. Gragera, A. Buschiazzo, D. Herreros, S. Bonn, R. Melero, C.O.S. Sorzano, J. M. Carazo, O. Medalia, A. Plückthun. Structural analysis of HER2-TZB complex reveals receptor conformational adaptation variability. (submitted)
249. E. Ulzurrun, A. Grande-Pérez, S. Rodríguez-Santana, D. del Hoyo, C.B. Guevara, C. Gil, C.O.S. Sorzano, N. Campillo. Unlocking the puzzle: Non-defining mutations in SARS-CoV-2 proteome may affect vaccine effectiveness. (submitted)
250. K.B. Lauer, R. David, J. Ewbank, N. Van Goethem, E. Harrison, N. Blomberg, E. Bernal-Delgado, P. Quinlan, S. Sansone, A. Lister, P. Rocca-Serra, S. Soiland-Reyes, N. Juty, F. Aarestrup, F. Zambelli, P. Holub, E. Garcia-Alvarez, R. Wittner, M. Panagiotopoulou, M.A. Tangaro, P. Gribbon, D. Yuan, G. Pesole, Graziano, I. Kemmer, S. Capella-Gutierrez, J. Lischke, R. Navest, J. Belien, M. Mayrhofer, M. Perola, K. Öjefors Stark, L. Hughes, T. Giles, C. Goble, K. Moilanen, L. Pireddu, S. Leo, C. Martin, R.A. Buono, V. Kalaitzi, S. Saldner, J.M. Carazo, C.O.S. Sorzano, A. Mathur, J. Rambla, A. Jené, B. Singh, A. Navarro, M. Ostaszewski, F. Messina, M. Lavitrano, C.E. Cocuzza, P. Romano, O. Colman, P. Gormannns, H. Hermjakob. Beyond COVID - how the BY-COVID project is increasing European pandemic preparedness. (submitted)
251. L. Guerrero, J. Vindel-Alfageme, L. Hierro, L. Stark, D. Vicent, C.O.S. Sorzano, F. Corrales. Discrimination of etiologically different cholestasis by machine learning-based modeling of proteomics datasets. (submitted)
252. D. Fry, M. Berdoy, M. Forni, T. Steckler, C.O.S. Sorzano, N. Franco. Effective experimental design education: learning outcomes and guidance from the FELASA Experimental Design Working Group. (submitted)
253. C.O.S. Sorzano, D.G. Hamilton, E. Mendez. Animal researchers' views on the publication of negative results and subsequent policy adoptions. (submitted)
254. J.R. Macías, C. Simón Guerrero, M. Martínez, C.O.S. Sorzano, J.M. Carazo. COVID-19 Structural Hub facilitates access to SARS-CoV-2 structural biology data. (submitted)

1. C.O.S.Sorzano, R.Marabini, J.M.Carazo, E.Rietzel, R.R.Schroder, G.T.Herman, N.Boisset. Effects of uneven sampling in 3D reconstructions. Proc. of the 14th International Congress on Electron Microscopy (1998), Vol I (771-772).
2. E.Rietzel, P.Schorsch, H.Muller, R.Marabini, C.O.S.Sorzano, J.M.Carazo, U.Schimpf, C.Leue, K.C.Holmes, R.R.Schroder. Zero-loss P-contrast in EFTEM . Proc. of the 14th International Congress on Electron Microscopy. (1998), Vol IV(421-422).
3. C.O.S.Sorzano, R. Marabini, N. Boisset, E.Rietzel, R.R.Schroder, G.T.Herman, J.M.Carazo. Quantitative comparison of 3D reconstruction algorithms under conditions of uneven angular distribution in electron microscopy. Proc. of the 1999 International meeting on fully 3D image reconstruction in Radiology and Nuclear Medicine (1999), 267-270.
4. J.M. Carazo, N. Jimenez-Lozano, C.O.S. Sorzano, M. Chagoyen. Towards more quantitative results from Three Dimensional Electron Microscopy of Macromolecules. Proc. of the 12th European Congress on Electron Microscopy (2000), Vol III (375-377).
5. J.A. Velazquez Muriel, C.O.S.Sorzano, J.M.Carazo. Method development of combination of atomic force and electron microscopy data to obtain better 3D reconstructions . Proc. of the Spanish, Portuguese and French Microscopy Societies meeting at Barcelona. (2001).
6. C.O.S.Sorzano, J.J. Fernandez, R. Marabini, G.T. Herman, Y. Censor, J.M. Carazo. Transfer function restoration in 3D electron microscopy via iterative data refinement. Proc. of the 2001 International meeting on fully 3D image reconstruction in Radiology and Nuclear Medicine (2001), 133-136.
7. C.O.S. Sorzano, R. Marabini, J. J. Fernandez, J. A. Velazquez-Muriel, G. T. Herman, J. M. Carazo. New reconstruction conditions greatly improve the reconstruction quality. Proc. of the 15th International Congress on Electron Microscopy (2002), Vol. 3, 431-432.
8. J.A. Velazquez Muriel, C.O.S. Sorzano, J.J. Fernandez, J. M. Carazo. 2D ARMA models and parameter adjustment to estimate the CTF of the electron microscope. Proc. of the 15th International Congress on Electron Microscopy (2002), Vol. 3, 433-434.
9. M.G. Gomez-Lorenzo, M. Valle, L.E. Donate, C. Gruss, M. Barcena, C.O.S. Sorzano, J. Frank, J.M. Carazo. Structural studies of SV40 large T-antigen on the origin of replication. Proc. of the 15th International Congress on Electron Microscopy (2002), Vol. 2.
10. C.O.S. Sorzano, R. Marabini, G. T. Herman, J. M. Carazo. Volumetric constraints in 3D tomography applied to electron microscopy. Proc. of the 1st International Symposium on Biomedical Imaging ISBI2002 (2002), 641-644.
11. R. Marabini, C. O. S. Sorzano, J.J. Fernandez, S. Matej, J.M. Carazo, G.T. Herman. 3D Reconstruction of 2D crystals from projections in real space. Proc. of the 1st International Symposium on Biomedical Imaging (2002), 689-692.
12. C.O.S. Sorzano. Angular assignment in 3D Electron Microscopy using PCA and wavelet decomposition . Proc. of the RMSE-AMS joint conference (2003), Session 37, 5.
13. J.M. Carazo, J.J. Fernandez, G.T.Herman, S. Matej, R. Marabini, C.O.S. Sorzano. Algebraic reconstruction of 2D crystals from their projections. Proc. of the RMSE-AMS joint conference (2003), Session 37, 4.
14. G.T.Herman, R. Marabini, C.O.S. Sorzano, J. Zubelli. Reconstruction by Chahine's method from Projections corrupted by Electron Microscope aberrations. Proc. of the RMSE-AMS joint conference (2003), Session 37, 5.
15. C.O.S.Sorzano, P. Thevenaz, S. Jonic, C. El-Bez, S. De Carlo, J. Conway, B. L. Trus, M. Unser. Volumetric Spectral Signal-to-Noise Ratio. Proc. of the 13th European Microscopy Congress, Vol. I, 427-428 (2004)
16. C.O.S.Sorzano, M. Blagov, P. Thevenaz, E. Myasnikova, M. Samsonova, M. Unser. Algorithm for spline-based elastic registration in application to confocal images of gene expression. Proc. of the 7th Intl. Conference on Pattern Recognition and Image Analysis, Vol. 3: 928-931 (2004)
17. G. Cañadas, M. Fernandez-Lopez, R. Garcia-Garcia, M. Lama, A. Sanchez-Alberca, C.O.S. Sorzano. Framework for automatic generation of ontology mappings. Jornadas Iberoamericanas de Ingenieria del Software e Ingenieria del Conocimiento Vol I: 293-304 (2004)
18. S. Jonic, C.O.S. Sorzano, P. Thevenaz, M. Unser, N. Boisset. Spline-Based approach to orientation assignment for three-dimensional electron microscopy. Proc. of Imaging for medical and life sciences Symposium (Imvie2) Vol I: 40-42 (2005)
19. S.H.W. Scheres, A.J. Merino, C.O.S. Sorzano, J.M. Carazo. Grid computing in 3D Electron Microscopy Image Processing using Xmipp. 18th IEEE Intl. Symposium on Computer-Based Medical Systems (CBMS) (2005)
20. M. Chagoyen, C.O.S. Sorzano, P. Carmona-Saez, J.M. Carazo, A. Pascual-Montano. Relating discrete annotation schemes in the functional space through literature analysis. Proc. of the 13th Annual Intl. Conference on Intelligent Systems in Molecular Biology (2005)
21. S.H.W. Scheres, R. Marabini, C.O.S. Sorzano, G.T. Herman, J.M. Carazo. Maximum-likelihood refinement of electron microscopy images. Gordon Research Conference (2005)
22. I. Arganda-Carreras, C.O.S. Sorzano, R. Marabini, J.M. Carazo, C. Ortiz-de-Solorzano. Skeleton-based 3D reconstruction of histological sections. Proc. of the Intl. Conference on Biomedical Visualization, MediViz (2005)
23. A. Sanchez-Alberca, R. Garcia-Garcia, C.O.S. Sorzano, C. Gutierrez-Cossio, M. Chagoyen, M. Fernandez-Lopez. AMON: A Software System for Automatic Generation of Ontology Mappings.  Workshop on Building and Applying Ontologies for the Sematic Web (BAOSW'05)  (2005)
24. C.O.S. Sorzano, J. Rodrigo, E. Ortiz, M. Lopez. Note on "Wavelets, Gaussian mixtures and Wiener filtering". Congreso Anual de la Sociedad Española de Ingenieria Biomedica, CASEIB2005, (2005)
25. C. Perez Gandia, G. Garcia-Saez, A. Rodriguez Herrero, M.E. Hernando Perez, C.O.S. Sorzano, E.J. Gomez Aguilera, F. del Pozo Guerrero. Metodologia de evaluacion de modelos de prediccion de glucemia en pacientes diabeticos basados en redes neuronales. Congreso Anual de la Sociedad Española de Ingenieria Biomedica, CASEIB2005 (2005)
26. B. Telenczuk, M.J. Ledesma-Carbayo, J.A. Velazquez-Muriel, C.O.S. Sorzano, J.M. Carazo, A. Santos. Molecular image registration using mutual information and differential evolution optimization. Proc. of the Third Intl. Syposium on Biomedical Imaging, ISBI2006 (2006)
27. I. Arganda-Carreras,  C.O.S. Sorzano, R. Marabini, J.M. Carazo, C. Ortiz-de-Solorzano, J. Kybic. Consistent and elastic registration of histological sections using vector-spline regularization. 2nd Intl. Workshop on Computer Vision Approaches to Medical Image Analysis, CVAMIA2006
28. C.O.S. Sorzano, P. Thevenaz, I. Valdes, A. Beloso, M. Unser. Elastic image registration with applications to Proteomics. Proc. of the Vth International Workshop on Information Optics: 300-309 (2006)
29. C. Messaoudi, S. Marco, C.O.S. Sorzano, T. Boudier. Evaluation of multiple-axis tomography in Tomo-J, a freeware plugin for the Java based public software ImageJ. Intl. Microscopy Congress (2006)
30. C. Messaoudi, S. Halary, C.O.S. Sorzano, S. Marco, T. Boudier. TomoJ: new tools for electron tomography. Proc of the Conf. on ImageJ: 155-161 (2006)
31. S. Jonic, C.O.S. Sorzano, M. Cottevieille, E. Larquet, N. Boisset. Improvement of visibility of diffraction rings for classification of micrographs and their local areas. Gordon Research Conference (2006)
32. S. Jonic, C.O.S. Sorzano, M. Cottevieille, E. Larquet, N. Boisset.  Nouvelle approche de visualisation et tri des diffractogrammes de cryo-MET base sur l'anistropie. Proc. of the 20th Conference of the French Biophysical Society: 171, (2006)
33. A. Iriarte-Ruiz, R. Marabini, C.O.S. Sorzano. Probabilidad de deteccion en camaras PET de detectores continuos. Congreso Anual de la Sociedad Española de Ingenieria Biomedica, CASEIB2006 (2006)
34. C.O.S. Sorzano, M.C. Perez-Gandia, A. Otero. Mathematical models in image processing. Proc. 1st Intl. Congress of Mathematics in Engineering and Architecture, 307-315 (2007, invited speaker)
35. M. Cottevieille, S. Jonic, C.O.S. Sorzano, E. Larquet, N. Boisset. 3D reconstruction of macromolecular assemblies at subnanometric resolution. Proc. 3rd Serbian Congress of Microscopy (2007)
36. S. Jonic, C.O.S. Sorzano, N. Boisset. 3D transmission electron microscopy of biological nanomachines. Proc. 3rd Serbian Congress of Microscopy (2007)
37. S. Jonic, C.O.S. Sorzano, M. Cottevieille, E. Larquet, C. Venien-Bryan, N. Boisset. Enhanced diffractograms for image sorting and improvement of robustness and accuracy of CTF estimation: Application on high-resolution reconstruction of glutamate synthase and phosphorilase kinase. Gordon Conference (2007)
38. A. Otero, P. Felix, F. Palacios, C. Perez-Gandia, C.O.S. Sorzano. Intelligent alarms for patient supervision. Proc. 5th Intl. Syposium on Intelligent Signal Processing, WISP: 157-162 (2007)
39. A. Otero, P. Felix, J. M. Rodriguez, C. Zamarron, C.O.S. Sorzano, C. Perez-Gandia. Algoritmos estructurales basados en logica borrosa para la identificacion de apneas e hipoapneas. Actas Congreso Anual de la Sociedad Española de Ingenieria Biomedica, CASEIB2007, (2007).
40. A. Otero, C.O.S. Sorzano, E.M. Olmos, P. Felix, M.R. Alvarez, C. Zamarron. A Fuzzy Constraint Satisfaction Approach to Identify and Characterize Apnea Episodes. 2nd Intl. Conference in Bioinformatics and Biomedical Engineering (iCBBE2008), Shangai, China. 2024-2027, (2008).
41. L. Fernandez-de-Manuel, M.J. Ledesma-Carbayo, J. Atienza-Herrero, C.O.S. Sorzano, J.M. Carazo, A. Santos. Flexible fitting of protein models into 3D-EM maps by using an image registration algorithm. International Symposium on Structural Analysis of Supramolecular Assemblies by Hybrid Methods (2008)
42. L. Fernandez-de-Manuel, M.J. Ledesma-Carbayo, J. Atienza-Herrero, C.O.S. Sorzano, J.M. Carazo, A. Santos. Flexible image registration for the identification of best fitted protein models in 3D-EM maps. Proc. Intl. Syposium on Biomedical Imaging, ISBI: 983-986 (2008)
43. C. Perez Gandia, M. E. Hernando, C.O.S. Sorzano, A. Otero Quintana, G. Garcia Saez, A. Rodriguez Herrero, B. M. Rigla, A. de Leiva, E. J. Gomez. Neural networks for glucose prediction in continuous glucose monitoring. Proc. of Advanced Technologies and treatments of diabetes. (2008)
44. S. Jonic, C.O.S. Sorzano, F. Tama, E. Larquet, N. Boisset. A hybrid method coupling normal mode analysis with projection matching to study structural flexibility of macromolecular assemblies. Gordon Research Conference on Three Dimensional Electron Microscopy, (2008).
45. I. Arganda-Carreras, C.O.S. Sorzano, J. Kybic, C. Ortiz de Solorzano. bUnwarpJ: Consistent and elastic registration in ImageJ. Methods and applications. ImageJ Conference Users-Developers (2008)
46. C.O.S. Sorzano, C. Messaoudi, M. Eibauer, R. Hegerl, R. Marabini, S. Nickell, S. Marco, J.M. Carazo. Registration of electron tomography single-axis tilt series without fiducial markers. Joint Spanish Portuguese Microscopy Congress: 215-216 (2009)
47. D. Bravo-Alcobendas, C.O.S. Sorzano. Clustering of biomedical scientific papers. IEEE Workshop on Intelligent Signal Processing (2009)
48. C.O.S. Sorzano, A. Iriarte, R. Marabini, J.M. Carazo. Effects of the downsampling scheme on three-dimensional electron microscopy of single particles.  IEEE Workshop on Intelligent Signal Processing (2009)
49. S. Jonic, C.O.S. Sorzano, F. Tama, E. Larquet, N. Boisset. A hybrid method coupling normal mode analysis with projection matching to study structural flexibility of macromolecular assemblies. Proc. 11th Congress of the French Society of Microscopies, (2009)
50. J.M. Carazo, S.H.W. Scheres, C.O.S. Sorzano. Understanding the dynamics of macromolecular machines by Three-Dimensional Electron Microscopy: The methods and some of their applications. Critical Assessment of Predicted Interactions (2009).
51. M. Li, G. Xu, C.O.S. Sorzano, R. Melero, C. Bajaj. Electric-potential reconstructions of single particles using L2-gradient flows. 3rd Intl. Conf. on BioMedical Engineering and Informatics (2010).
52. R. Marabini, J. Oton, R. Navarro, C.O.S. Sorzano, J.M. Carazo. X-ray tomography: an image formation model. Annual meeting of the Nordic Microscopy Society Scandem (2010)
53. J.M. Carazo, S.H.W. Scheres, C.O.S. Sorzano. Understanding the dynamics of macromolecular machines by Three-Dimensional Electron Microscopy: The methods and some of their applications. Annual meeting of the Nordic Microscopy Society Scandem (2010).
54. J. Oton, C.O.S. Sorzano, J.M. Carazo, R. Marabini. First considerations on the reconstruction of X-ray tomography. Intl. Microscopy Congress (2010)
55. J. Oton, R. Marabini, C.O.S. Sorzano, J.M. Carazo. Limitations in 3D reconstruction of X-ray tomography. Intl. Microscopy Congress (2010)
56. A. Alvarez-Cabrera, C.O.S. Sorzano, J. Busselez, R. Gonzalez, Z. You, J.M. Carazo. Structural analysis of the Mouse MCM4/6/7 helicase in complex with Cdt1. Proc. XXXIII Congreso de la Soc. Española Bioquimica y Biologia Molecular (2010)
57. A. Quintana, C.O.S. Sorzano, R, Marabini, J.M. Carazo. Benchmarking for 3D Electron Microscopy. X Jornadas de Bioinformatica (2010)
58. J.Oton, R. Marabini, C.O.S.Sorzano, J.M.Carazo. X-ray Cellular Tomography: How the images are formed and how the volumes should be reconstructed. EMBL 6th Intl. Congress on Electron Tomography (2011)
59. A. Deideri, G. Caffarena, J.A. Lopez, C.O.S. Sorzano. Acceleration of Electron Microscopy applications with GPGPUs and FPGAs. XI Jornadas de Computacion Reconfigurable y Aplicaciones (2011)
60. A.G. Goodman, S. Guerra, A. Vijayan, P.P. Heinen, C.O.S. Sorzano, M. Esteban. A recombinant Vaccinia virus-based T cell vaccine against influenza virus reduces lung viral load upon virus challenge. Gene and Cell Therapy Conference (2011)
61. J. Garcia-Arriaza, J.L. Najera, C.E. Gomez, N. Tewabe, C.O.S. Sorzano, T. Calandra, T. Roger, M. Esteban. A candidate HIV/AIDS vaccine (MVA-B) that enhances the magnitude and polyfunctionality of memory HIV-1-specific T-cell responses. AIDS Vaccine (2011)
62. R. Marabini, J. Oton, C.O.S. Sorzano, J.M. Carazo. X-ray Cellular Tomography: How the images are formed and how the volumes should be reconstructed. 2nd Microscopy Congress of the Portuguese and Spanish Societies (2011)
63. R. Marabini, J.M. de la Rosa-Trevin, J. Cuenca, A. E. Rey, J. Vega, J. Oton, C.O.S. Sorzano, J.M. Carazo. Xmipp 3.0: a specialized suite for image processing in microscopy. 2nd Microscopy Congress of the Portuguese and Spanish Societies (2011)
64. C.O.S. Sorzano, J. Oton, J. Cuenca, A. Zaldivar-Perez, G. Caffarena, J. Sanchez-Jimenez, C. Messaoudi, S. Marco, R. Marabini, J.M. Carazo. Image processing for Cellular tomography using soft X-rays. 9th Intl. Symposium on Biomedical Imaging (2012, Invited talk)
65. C.O.S. Sorzano, J. Cuenca, J. Sanchez-Jimenez, C. Messaoudi, J.M. Carazo. Java-C++ hybrid image processing using ImageJ: an example in electron and X-rays tomography Xmipp-TomoJ. Bioimage Analysis Workshop (2012, Invited talk)
66. C.O.S. Sorzano, R. Marabini. J.M. Carazo. Three-dimensional Electron Microscopy: Current challenges. Workshop on BioNMR (2012, Invited talk)
67. I. Sanchez-Caballero, A. Muniategui, R. Nogales-Cadenas, C.O.S. Sorzano, A. Rubio, A. Pascual-Montano. Improving microRNA target prediction by performance-based algorithm combination. Jornadas de Bioinformatica (2012)
68. A. Quintana, J. Vargas, A. Poza, J.R. Macias, R. Marabini, C.O.S. Sorzano, J. M.Carazo. Scipion: Towards electron microscopy integration. Jornadas de Bioinformatica (2012)
69. C. Messaoudi, N. Ashman, M. Lyra Da Cunha, T. Oikawa, C.O.S. Sorzano, S. Marco. Improving EFTEM 3D Chemical maps by multivariant statistical analysis and iterative denoising. 15th European Microscopy Congress (2012)
70. R. Marabini, A. Quintana, C.O.S. Sorzano, J.M. Carazo. Benchmarking and Standardization for 3D Electron Microscopy. Gordon Research Conference (2012)
71. J.M. de la Rosa-Trevin, R. Marabini, J. Oton, A. Zaldivar-Peraza, J. Vargas, J.M. Carazo, C.O.S. Sorzano. Xmipp 3.0: Advances in image processing for 3D Electron Microscopy of Single Particles. Gordon Research Conference (2012)
72. T. Bharat, S.G. Wolf, D. Zbaida, C.O.S. Sorzano, M. Eisenstein, M. Elbaum. Quaternary structural flexibility of VirE2 is intrinsic and functionally relevant in DNA transfer by A. tumefaciens. Meeting of the Israel Soc. for Microscopy (2012)
73. T.O. Mendes, C.O.S. Sorzano, S. Angulo, M.J.V. Bell, F.J. Ruperez, C. Barbas. Controlled experiment for evaluation of statistical models for data analysis in Metabolomics. XII Reunion Cientifica de la Sociedad Española de Tecnicas de Cromatografia y Afines (SECYTA) (2012)
74. A. Muniategui, I. Sanchez-Caballero, R. Nogales-Cadenas, C.O.S. Sorzano, A. Pascual-Montano, A. Rubio. Integration of disparate sources of information to predict miRNA-mRNA interactions. qPCR & NGS Symposium (2013)
75. D.J. Martinez-Herrera, D. Tabas-Madrid, C.O.S. Sorzano, A. Pascual-Montano. Computational estimation of microRNA targets and binding site frequencies. Annual Intl. Conf. Intelligent Systems for Molecular Biology (ISMB) (2013)
76. J. Oton, C.O.S. Sorzano, R. Marabini, J.M. Carazo. Three-dimensional reconstruction in Soft X-ray Tomography. Annual Meeting of the Nordic Microscopy Society (2013)
    
77. Q. Jin, C.O.S. Sorzano, J.M. Delarosa-Trevin, J.R. Bilbao-Castro, R. Nuñez-Ramirez, O. Llorca, F. Tama, S. Jonic. Normal mode analysis for electron microscopy revitalized. Gordon Research Conference: Three-dimensional Electron Microscopy (2013).
78. J. Vargas, R. Marabini, J.M. de la Rosa-Trevin, A. Zaldivar-Peraza, J.M. Carazo, C.O.S. Sorzano. The use of the spiral phase transform in 3DEM. Microscopy at the frontiers of science (2013)
    
79. C.O.S. Sorzano, J. Vargas, J.M. de la Rosa-Trevin, A. Zaldivar-Peraza, J. Oton, V. Abrishami, I. Foche, R. Marabini, G. Caffarena, J.M. Carazo. Outlier detection for single particle analysis in Electron Microscopy. International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO, 950 (2014)
80. E. Garcia, M. Mateo, A. Deideri, C.O.S. Sorzano, A. Iriarte, G. Caffarena. 2D and 3D alignment for Electron Microscopy via Graphics Processing Units. International Work-Conference on Bioinformatics and Biomedical Engineering IWBBIO, 960 (2014)
    
81. V. Abrishami, J. Vargas, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Alignment of Direct Detector Device micrographs using a local least-squares approach. 18th Intl. Microscopy Congress (2014)
82. C. Messaoudi, N. Aschman N, M. Cunha, T. Oikawa, C.O.S. Sorzano, J.J. Conesa, M. Chiappi, E. Pereiro, F.J. Chichon, J.L. Carrascosa, S. Marco. EFTEM-TomoJ : software for 3D chemical mapping by EFTEM and soft X-ray NEXAFS tomography. 18th Intl. Microscopy Congress (2014)
83. R. Barroso, C.O.S. Sorzano, J. Vargas, V. Rocha-Perugini, J.L. Rodriguez-Fernandez, I. Gonzalez, F. Sanchez-Madrid, L. Martinez-Muñoz, M. Mellado. CXCL2 and the actin cytoskeleton regulate CXCR4 lateral mobility and clustering. SIICA - SSAI Joint Workshop on Imaging the Immune System (2014)
84. C.O.S. Sorzano, J. Vargas, J. Oton, V. Abrishami, J.M. de la Rosa-Trevin, S. del Riego, A. Fernandez-Alderete, C. Martinez-Rey, R. Marabini, J.M. Carazo. An image processing approach to the simulation of electron microscopy volumes and images of atomic structures. IEEE Conference on Image Processing (ICIP2014), 2095 - 2099 (2014)
85. Q. Jin, C.O.S. Sorzano, I. Callebaut, F. Tama, S. Jonic. Elastic image registration to fully explore macromolecular dynamics by electron microscopy. IEEE Conference on Image Processing (ICIP2014), 2075 - 2079 (2014)
86. J. Vargas, R. Marabini, J.M. Carazo, C.O.S. Sorzano. Efficient initial volume determination using RANSAC algorithm. Cryo-EM Image Analysis Symposium (2014)
87. Q. Jin, C.O.S. Sorzano, J.M. de la Rosa-Trevin, J.R. Bilbao-Castro, R. Nuñez-Ramirez, O. Llorca, F. Tama, S. Jonic. HEMNMA: Hybrid Electron Microscopy Normal Mode Analysis to fully explore macromolecular dynamics. Cryo-EM Image Analysis Symposium (2014)
88. R. Marabini, J. Vargas, C.O.S. Sorzano, W. Jiang, K. Downing, W. Chiu, J.M. Carazo. Preliminary analysis of the CTF challenge results. Gordon Research Conference: Three-dimensional Electron Microscopy (2014)
89. C. Messaoudi, N. Aschman, M. Cunha, T. Oikawa, C.O.S. Sorzano, J.J. Conesa, M. Chiappi, E. Pereiro, F.J. Chichon, J.L. Carrascosa, S. Marco. 3D chemical mapping by EFTEM and XANES tomography using EFTEM-TomoJ. Intl. Microscopy Congress (2014)
90. Q. Jin, C.O.S. Sorzano, J.M. de la Rosa-Trevin, F. Tama, S. Jonic. Macromolecular dynamics by hybrid electron microscopy normal mode analysis. Microscopy and Microanalysis (2014)
91. A. Iriarte, G. Caffarena, M. Fernandez, R.G. Carmona, A. Otero, C.O.S. Sorzano, R. Marabini. Iterative Reconstruction for PET scanners with continuous detectors. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (2015)
92. C.O.S. Sorzano, J.M. de la Rosa-Trevin, J. Oton, A.L. Alvarez-Cabrera, J. Vargas, R. Marabini, J.M. Carazo. Robust construction of initial volumes. Gordon Research Conference: Three-dimensional Electron Microscopy (2015)
93. C.O.S. Sorzano, A.L. Alvarez-Cabrera, J.M. Carazo, S. Jonic. StructMap: Multivariate distance analysis of elastically aligned electron microscopy structures for exploring pathways of conformational changes. Gordon Research Conference: Three-dimensional Electron Microscopy (2015)
94. C.O.S. Sorzano, A.L. Alvarez-Cabrera, J.M. Carazo, S. Jonic. StructMap: New way of looking at the discrete- versus continuous-flexibility problem in molecular electron microscopy . Cryo-EM 3D Image Analysis Symposium (2016)
    
95. J. Vargas, C.O.S. Sorzano, J.M. Carazo. Soft alignment validation in cryo-electron microscopy. Cryo-EM 3D Image Analysis Symposium (2016)
    
96. C.O.S. Sorzano, J.M. Carazo, A. Pascual-Montano, M. Franch, M. Martinez. Meta-analysis in rare diseases: getting the most from scarce microarray experiments. XIII Symposium on Bioinformatics (2016)
    
97. R. Sanchez-Garcia, J. Segura, J. Cuenca-Alba, C.O.S. Sorzano, J.M. Carazo. Machine learning-based method for residue-residue contact prediction. XIII Symposium on Bioinformatics (2016)
    
98. J.M. Carazo, J.L. Vilas, J. Gomez-Blanco, P. Conesa, R. Melero, J.M. de la Rosa-Trevin, J. Oton, J. Cuenca, R. Marabini, J.Vargas C.O.S. Sorzano. Automatic calculation of Local Resolution with MonoRes: A new approach, its assessment and new applications.. 5th Joint Congress of the Portuguese and Spanish Microscopy Societies.(2017)
    
99. R. Sanchez-Garcia, J. Segura, C.O.S. Sorzano, J.M. Carazo. Residue-residue contact prediction based on a random forest multi-step approach.. Basel Computational Biology Conference (2017)
    
100. J. Segura, R. Sanchez-Garcia, D. Tabas Madrid, C.O.S. Sorzano, J.M. Carazo. 3DBionotes: Unifying genomics and molecular biology data. Biotec (2017)
     
101. R. Moieni, P. Mousaferiadis, C.O.S. Sorzano. A Practical Approach to Measuring Cultural Diversity on Australian Organizations and Schools. 7th Intl. Conf. on Humanities, Society and Culture (2017)
     
102. J.M. Carazo, J.L. Vilas, J. Vargas, C.O.S. Sorzano. Reconstructing macromolecular structures to quasi-atomic resolution with Scipion. Protein Structure Determination in Industry (2017)
     
103. A. Gomez Lopez, Y. Mozo, B. Rosich del Cacho, D. Bueno, A. Escudero, I. Mirones, A. Fernandez-Arroyo, A. Sastre, C.O.S. Sorzano, A. Perez-Martinez. Predicting outcomes after pediatric stem cell transplantation for hematological malignancies: a decision-tree-based model. 44th Annual Meeting of the European Soc. for Blood and Marrow Transplantation (EBMT 2018) (2018)
     
104. M. Kazemi, C.O.S. Sorzano, J.M. Carazo, J. Vargas. Improving 3D reconstructions of macromolecular conformations. 3rd International Symposium on Cryo-3D Image Analysis (2018)
     
105. C.O.S. Sorzano, J. Vargas, J.L. Vilas, A. Jimenez, J.M. Carazo. High-resolution reconstructions and local-directional resolution. 3rd International Symposium on Cryo-3D Image Analysis (2018)
     
106. R. Marabini, J.L. Vilas, H. Tagare, J.M. Carazo, J. Vargas, C.O.S. Sorzano. Directional-local resolution, perspectives, and potential beyond the structural elucidation. Gordon Research Conference on Three-dimensional Electron Microscopy (2018)
     
107. J. Segura, R. Sanchez, C.O.S. Sorzano, J.M. Carazo. 3DBIONOTES crossing genomics, proteomics and interactomics. European Conf. on Computational Biology (2018)
     
108. M. Iriondo DeHond, A. Iriondo DeHond, T. Herrera, C.O.S. Sorzano, E. Miguel, M.D. del Castillo. Randomized cross-over nutritional trial of yogurts containing dietary-fiber and coffee cascara extract in healthy adults. Nutrimad (2018)
     
109. R. Sanchez-Garcia, J. Segura, D. Maluenda, C.O.S. Sorzano, J.M. Carazo. Deep consensus: deep learning for particle pruning in cryo-electron microscopy. Jornadas de Bioinformatica (2018)
     
110. J. Segura, R. Sanchez-Garcia, C.O.S. Sorzano, J.M. Carazo. 3DBIONOTES: crossing molecular biology. Jornadas de Bioinformatica (2018)
     
111. M.Q. Marin, P. Perez, C.O.S. Sorzano, K. Ljunberg, P. Liljestrom, C.E. Gomez, M. Esteban, J. Garcia-Arriaza. Immunization with DNA-launched RNA Replicon and Poxvirus Vaccine Candidates Expressing HCV Proteins Induce Potent Immune Responses. 25th International Symposium on Hepatitis C Virus and Related Viruses, Dublin, (2018)
     
112. P. Perez, M.Q. Marin, A. Lazaro-Frias, N. Jimenez de Oya, A.B. Blazquez, E. Escribano-Romero, C.O.S. Sorzano, J. Ortego, J.C. Saiz, M. Esteban, M.A. Martin-Acebes, J. Garcia-Arriaza. A Vaccine Based on a Modified Vaccinia Virus Ankara Vector Expressing Zika Virus Structural Proteins Controls Zika Virus Replication in Mice. Enable Conference, Copenhagen, (2018)
     
113. B. Ruz-Caracuel, A. Escudero-Lopez, C.O.S. Sorzano, A. Perez-Martinez. Algoritmos pronósticos de riesgo de mortalidad post-transplante hematopoyetico pediatrico. XII Congreso de la Sociedad Española de Hematologia y Oncologia Pediatricas (2019)
     
114. J.L. Vilas, H.D. Tagare, P. Conesa, R. Sanchez, R. Melero, J. Oton, C. Meassaudi, A. Jimenez, M. Martinez, D. Maluenda, E. Ramirez-Aportela, R. Marabini, J.M. Carazo, J. Vargas, C.O.S. Sorzano. A local resolution in electron tomography and local directional resolution in Single Particle Analysis. Gordon Research Conference Three Dimensional Electron Microscopy (2019)
     
115. C.O.S. Sorzano, J.L. Vilas, P. Conesa, R. Sanchez, R. Melero, A. Jimenez, L. Del Caño, Y. Fonseca, P. Horvarth, M. Martinez, D. Maluenda, E. Ramirez-Aportela, R. Marabini, J.M. Carazo. Advances in Scipion and Xmipp for Single Particle Analysis by CryoEM. Gordon Research Conference Three Dimensional Electron Microscopy (2019)
     
116. E. Ramirez-Aportela, J.L. Vilas, C.O.S. Sorzano, J.M. Carazo. LocalDeblur: An automatic map sharpening by restauration of local resolution . Congress of the European Biophysical Societies' Association (2019)
     
117. J.R. Macías, C.O.S. Sorzano, J.M. Carazo. 3DBIONOTES: a set of analysis tools and integrated viewers to find relations between genomic variants and structural features. Elixir All hands (2020)
     
118. J.R. Macías, R. Sánchez García, P. Conesa, E. Ramírez-Aportela, M. Martínez, C.O.S. Sorzano, J.M. Carazo. 3DBionotes-COVID19 Edition: bringing together structural and functional information on SARS-CoV-2 proteome.European Conf. on Computational Biology (2020)
     
119. L. del Caño, P. Conesa, P. Audergon, N. Haley, J.M. Carazo, C.O.S. Sorzano. Increasing access to FAIR data and image processing workflows in Cryo Electron Microscopy within the European Open Science Cloud (EOSC). 3D Bioinformatics Annual Meeting (2020)
     
120. J.R. Macías, E. Ramírez-Aportela, R. Sánchez-García, P. Conesa, M. Martínez, C.O.S. Sorzano, J.M. Carazo. A newer set of annotations in 3DBionotes-WS. 3D Bioinformatics Annual Meeting (2020)
     
121. C.O.S. Sorzano, J.M. Carazo. Bias and variance in CryoEM. Keystone Virtual Conf. Frontiers in Cryo-Electron Microscopy (2021) Video
     
122. D. Herreros, R.R Lederman, J. Krieger, A. Jiménez-Moreno, M.Martínez, D. Myska, D. Strelak, J. Filipovic, I. Bahar, C.O.S. Sorzano, J.M. Carazo. Analysis of continuous flexibility made user friendly: A functional approach based on Zernike polynomials and Spherical harmonics. OneWorld Cryo-EM (2021)
     
123. J. Krieger, Y. Zhang, K. Mikulska-Ruminska, B. Kaynak, S. Zhang, H. Li, C.O.S. Sorzano, J.M. Carazo, J. Xing , I. Bahar. ProDy 2.0 and CryoDy: Extension of Protein Dynamics Analyses to Large Scale and Cryo-EM Maps. CCPEM Spring Symposium (2021)
     
124. D. Herreros, R.R Lederman, J. Krieger, A. Jiménez-Moreno, M.Martínez, D. Myska, D. Strelak, J. Filipovic, I. Bahar, C.O.S. Sorzano, J.M. Carazo. Continuous heterogeneity analysis of CryoEM images through Zernike polynomials and spherical harmonics. Microscopy and microanalysis (2021)
     
125. J. Jiménez, F. de Isidro, E. Fernández-Giménez, D. Herreros, Y. Fonseca, P. Conesa, A. Cuervo, J. Conesa, R. Melero, J.M. Carazo, C.O.S. Sorzano. Electron Tomography Workflows using Scipion. Microscopy and microanalysis (2021)
     
126. D. Herreros, R.R Lederman, J. Krieger, A. Jiménez-Moreno, M.Martínez, D. Myska, D. Strelak, J. Filipovic, I. Bahar, C.O.S. Sorzano, J.M. Carazo. A new simplified approach to study continuous heterogeneity based on Zernike Polynomials and Spherical Harmonics. Microscopy and microanalysis (2021)
     
127. A. Cayuela, C.O.S. Sorzano. Cell-Type Analyzer: A Fij/ImageJ plugin for detection, quantification and classification of fluorescent labeled single-cell according to user customization. PSB Symposium Frontiers in Bioimaging (2021)
     
128. J.R. Macias, R. Sanchez-Garcia, P. Conesa, E. Ramirez-Aportela, M. Martinez Gonzalez, C. Wert-Carvajal, A.M. Parra-Perez, J. Segura Mora, S. Horrell, A. Thorn, C.O.S. Sorzano, J.M. Carazo. 3DBionotes Covid-19 Edition. Elixir 3D Bioinfo Community Annual Meeting (2021)
     
129. A. Méndez-Pérez, C. Wert-Carvajal, R. Sánchez-García, J.R. Macías, R. Sanz-Pamplona, R. Alemany, C.O.S. Sorzano, A. Muñoz-Barrutia, E. Veiga. In vivo experimental validation of the novel online tool NAP-CNB, a platform to predict MHC-I restricted T cell tumor epitopes in mice European Congress of Immunology (2021)
     
130. C.O.S. Sorzano, A. Jiménez-Moreno, E. Ramírez-Aportela, J. Krieger, J. Filipovic, P. Conesa, Y.C. Fonseca, J. Jiménez-de la Morena, D. Strelak, E. Fernández-Giménez, F. de Isidro, D. Herreros, D. Marchán, J.L. Vilas, R. Marabini, J.M. Carazo. Why is a single execution of a single algorithm not enough in CryoEM? Microscopy at the Frontiers of Science (2021)
     
131. A. Cuervo, P. Losana, J.J. Conesa, C. Wang, J. Jiménez de la Morena, A. Plückthun, O. Medalia, C.O.S. Sorzano, J.M. Carazo. Implementation of a workflow for the structural characterization of HER2 by subtomogram averaging. Microscopy at the Frontiers of Science (2021)
     
132. E. Ramírez-Aportela, D. Maluenda, R. Melero, Y. Fonseca-Reyna, P. Conesa, J.M. Carazo, C.O.S. Sorzano. FSC-Q: A method for quality analysis of cryoEM-derived models. 25th IUCr Congress (2021)
     
133. J.R. Macías, E. Ramirez-Aportela, J.L. Vilas, M. Martínez, A.M. Parra-Pérez, C.O.S. Sorzano, J.M. Carazo. EMVS: A New Set of Annotations for cryo-EM Quality Validation Reports. Microscopy at the Frontiers of Science (2021)
     
134. M.A. Cuesta-Geijo, I. García Dorival, A. del Puerto, J. Urquiza, I. Galindo, L. Barrado-Gil, F. Lasala, A. Cayuela, C.O.S. Sorzano, C. Gil, R. Delgado, C. Alonso. New insights into the role of endosomal proteins for African swine fever virus infection. Viruses (2022)
     
135. D. Herreros, R.R Lederman, J. Krieger, A. Jiménez-Moreno, M.Martínez, D. Myska, D. Strelak, J. Filipovic, I. Bahar, C.O.S. Sorzano, J.M. Carazo. Zernikes3D: A new tool to study molecular motions through CryoEM particles. 4th Intl. Conference on Image Analysis in Three-dimensional Cryo-EM (2022)
     
136. D. Marchán, A. García-Mena, P. Conesa, F.J. Chichón, R. Arranz, Y. Fonseca-Reyna, L. del Caño, I. Sánchez-López, M. Iceta, J.M. Valpuesta, J.M. Carazo, C.O.S. Sorzano. Stream processing of CryoElectron Microscopy images at the acquisition site. Instruct Biennial Structural Biology Conf. (2022)
     
137. M.J. de Hita, C.O.S. Sorzano, M. Criado. Immobilization of spent nuclear grade resins in low carbon cement: study of the reaction kinetics. European Commission Conference on EURATOM Research and Training in Radioactive Waste Management. (2022) (poster)
     
138. D. Herreros, J. Krieger, C.O.S. Sorzano, J.M. Carazo. Macromolecular flexibility and its study though the new Zernikes3D bases coupled with Molecular Dynamics. Gordon Research Conference on 3D Electron Microscopy. (2022)
     
139. D. Herreros, J. Krieger, C.O.S. Sorzano, J.M. Carazo. Macromolecular flexibility and the experimental determination of conformational landscapes in the context of 3DBioinformatics. Intl. Work-Conference on Bioinformatics and Biomedical Engineering. (2022)
     
140. D. Herreros, J. Krieger, C.O.S. Sorzano, J.M. Carazo. New approaches to combine experimental information on macromolecular flexibility with Molecular Dynamics calculations. European Conference on Computational Biology (2022)
     
141. M. Criado, C.O.S. Sorzano, M.J. de Hita. Cinética de reacción de cementos activados alcalinamente para el almacenamiento de resinas gastadas de grado nuclear. 47ª Reunión Anual de la Sociedad Nuclear Española (2022)
     
142. J. Krieger, D. Herreros, C.O.S. Sorzano, J.M. Carazo. Extraction of continuous protein dynamics from CryoEM aided by coefficient conversion between normal modes and 3D Zernike polynomials. CCPEM Spring Symposium (2022)
     
143. J. Jiménez de la Morena, P. Conesa, Y.C. Fonseca, F.P. de Isidro-Gómez, D. Herreros, E. Fernández-Giménez, A. Cuervo, P. Losana, J.M. Carazo, C.O.S. Sorzano, J.L. Vilas. ScipionTomo: a standard framework for cryoelectron tomography image processing. 9th Electron Tomography Congress (2022)
     
144. M.J. de Hita, C.O.S. Sorzano, M. Criado. Effect of the incorporation of spent nuclear resins on the mechanical properties and porosity of alkali-activated slag – ash cement. 41st Cement and concrete science conference (2022)
     
145. C.E. Gómez, B. Perdiguero, M. Falqui, M.Q. Marín, M. Bécares, C.O.S. Sorzano, J. García-Arriaza, M. Esteban, S. Guerra Enhancement of HIV-1 Env-Specific CD8 T Cell Responses Using Interferon-Stimulated Gene 15 as an Immune Adjuvant. The ISG15 system in molecular function and disease mechanisms (2022)
     
146. J. Krieger, D. Herreros, C.O.S. Sorzano, J.M. Carazo. New Tools and Pipelines for Continuous Heterogeneity Analysis from Cryo-EM using Normal Modes and 3D Zernike Polynomials. European Crystallography Meeting (2022)
     
147. D. del Hoyo, E. Ulzurrun, N. Campillo, C.O.S. Sorzano. Scipion-Chem: a traversal tool for the development of antiviral drugs. Congreso de la PTI Salud Global (2022)
     
148. E. Ulzurrun, D. del Hoyo, M. Herrera, B. Navarro, P. Ruiz-Rodriguez, S. Rodrigez-Santana, D. Garcia-Resines, R. Naveiro, C. Gil, J.M. Carazo, M. Coscollá, C.O.S. Sorzano, N. Campillo. Bioinformatics analysis of mutations in SARS-CoV-2 and clinical phenotypes. Congreso de la PTI Salud Global (2022)
     
149. D. Herreros, R.R Lederman, J. Krieger, A. Jiménez-Moreno, M.Martínez, D. Myska, D. Strelak, J. Filipovic, S. Subramanian, C.O.S. Sorzano, J.M. Carazo. A new tool for the analysis of molecular motions: studying continuous heterogeneity through Zernikes3D. Gordon Research Conference on Three-dimensional Electron Microscopy (2022)
     
150. D. Herreros, R.R Lederman, J. Krieger, A. Jiménez-Moreno, M.Martínez, D. Myska, D. Strelak, J. Filipovic, S. Subramanian, C.O.S. Sorzano, J.M. Carazo. Pushing local resolution of reconstructed maps: ZART and heterogeneity-based motion blur corrections. Gordon Research Conference on Three-dimensional Electron Microscopy (2022)
     
151. P. Ruiz-Rodriguez, M. Álvarez-Herrera, M.L. Franco, C. Francés-Gómez, M.C. Marques, E. Ulzurum, F.J. Martínez-Martínez, S. Rodríguez Santana, R. Naveiro Flores, D. García Rasines, A. Marina, J.L. Llácer, Marçal Vidal, C.O.S. Sorzano, J.M. Carazo, C. Gil, D. Ríos, F. González-Candelas, R. Geller, I. Comas, S.F. Elena, M. Coscollá. Genomic surveillance and impact of SARS-CoV-2 mutations. Congreso de la PTI Salud Global (2022)
     
152. S. Rodríguez Santana, R. Naveiro, D. García Rasines, C. B. Guevara Maldonado, E. Ulzurrun, M. Álvarez-Herrera, P. Ruiz-Rodríguez, B. Navarro-Domínguez, C.O.S. Sorzano, M. Coscollá, N. Campillo Martín, D. Ríos Insua. SARS-CoV2 genomic statistical analysis to study hospitalization and vaccine failure. Congreso de la PTI Salud Global (2022)
     
153. J.M. Carazo, D. Herreros, C.O.S. Sorzano. Beyond discrete classes: Continuous flexibility analysis to better understand molecular motions and improuve resolutions by Zernike3D. Protein Structure Determination in Industry (2022)
     
154. C. Simón, J.R. Macías, E. Ramírez-Aportela, M. Martínez, C.O.S. Sorzano, J.M. Carazo. Imaging Data: adding a new type of annotations to 3DBionotes-WS. European Conference on Computational Biology (2022)
     
155. J.R. Macías, C. Simón, E. Ramírez-Aportela, J.L. Vilas, M. Martínez, C.O.S. Sorzano, J.M. Carazo. 3DBionotes COVID-19 Structural Hub: a central resource for validation information and refined models. European Conference on Computational Biology (2022)
     
156. C. Marco-Marín, C.P. Mata, T. Ginex, M. Wieczór, J. Krieger, M.L. López-Redondo, R. Melero, N. Gougeard, A. Forcada-Nadal, S. Zamora-Caballero, R. Gozalbo-Rovira, C. Sanz-Frasquet, M. Martínez, R. Arranz, C. Francés-Gómez, L. Villamayor, C. Espinosa, M.P. Fernández-Sierra, A. Adhav, R. Ruiz-Partida, J. Bravo, A. Marina, V. Rubio, C.O.S. Sorzano, R. Geller, C. Gil, M. Orozco, J.M. Carazo, J.L. Llácer. Biophysical and structural characterization of the Spike of the 20E (EU1) SARS-COV-2 variant. Congreso Soc. Española de Bioquímica y Biología Molecular (2022)
     
157. A. Cuervo, P. Losana, C. Wang, J.J. Conesa, J. Jiménez de la Morena, J.L. Vilas, P. Conesa, A. Martínez-Sánchez, A. Plückthun, O. Medalia, C.O.S. Sorzano, J.M. Carazo. Implementation of a workflow for the structural characterization of HER2 by subtomogram averaging. Electron Tomography Congress (2022)
     
158. L. del Caño, I. Sánchez, J.M. Carazo, C.O.S. Sorzano, T. Svoboda, R. Veverka, J. Handl, A. Krnek, J. Novacek. A FAIR and Cloud-enabled approach for Electron Microscopy data processing. EOSC Symposium (2022)
     
159. J. Krieger, D. Herreros, C.O.S. Sorzano, J.M. Carazo. Scipion-EM-ProDy: A Graphical Interface for the ProDy Python Package enabling Integration of Databases, Simulations and Cryo-Electron Microscopy Image Processing. 5th Manchester Multiscale Conference (2023)
     
160. J.G. Piccirillo, J.J. Conesa, A. Cayuela, D. Delgado-Gestoso, R. Arranz, F.J. Chichón, N. Zamarreño, M.T. Bueno-Carrasco, C.O.S. Sorzano, N.B. Martín Cófreces, F. Sánchez Madrid, J.M. Valpuesta. Implementation Data Processing Pipeline for Cryo FIBSEM Volume Imaging. Microscopy at the Frontiers of Science (2023)
     
161. P. Losana, J. Kowal, K. Nosol, D. Herreros, L. Hongtao, C.O.S. Sorzano, K.P. Locher, A. Cuervo, J.M. Carazo. Exploring Structural Flexibility and Classification Methods for Identifying Intermediate States of Hepatic ABCB Transporters. Microscopy at the Frontiers of Science (2023)
     
162. D. Herreros, R.R. Lederman, J. Kiska, J. Filipovic, C.O.S. Sorzano, J.M. Carazo. Zernike3Deep: Combining classic analytics and deep learning for flexibility analysis and resolution enhancement. Flatiron Institute CryoEM Summer Workshop (2023)
     
163. J.M. Krieger, D. Herreros, D. del Hoyo, Y. Fonseca, M. Gragera, C.P. Mata, A. Lomas, E. Ulzurrun, N.E. Campillo, P. Conesa, C.O.S. Sorzano, J.M. Carazo. Scipion flexibility hub and Scipion chem: new frameworks coupling computational biophysics of protein dynamics and virtual screening to cryo-electron microscopy. (submitted)
     
164. C.P. Mata, D. Herreros, J.M. Krieger, C.O.S. Sorzano, J.M. Carazo. Structural flexibility analysis of SARS-CoV-2 S protein in the context of the Omicron BA.2 variant of concern. (submitted)
     
165. E. Ulzurrun, S. Rodríguez-Santana, D. del Hoyo, A. Grande-Pérez, C.B. Guevara, C. Gil, C.O.S. Sorzano, N. Campillo. Bioinformatic analysis of mutations in the whole proteome of SARS-CoV-2 and their role in vaccine effectiveness (submitted)
     
166. O. Zarrabeitia, E. Ramírez-Aportela, J.M. Carazo, C.O.S. Sorzano. Fast global image alignment algorithm for CryoEM through vector compression (submitted)
     
167. D. Fry, M. Berdoy, M. Forni, T. Steckler, C.O.S. Sorzano, N.H. Franco. Improving education on the experimental design of animal studies – Contributions by a FELASA Working Group. SPCal Annual Conf.(2024)
     

Non peer-reviewed articles articles

1. C.O.S. Sorzano. Elastic registration with vector-spline regularization. Seminario de modelizacion matematica en imagen medica, UNED (2007) (video)
2. C.O.S. Sorzano, C. Bocos de Prada. Biotecnologia Computacional (version extendida). EPS CEU Internal report.
3. C.O.S. Sorzano, C. Bocos de Prada. Biotecnologia Computacional. Bit (Revista del Colegio de Ingenieros de Telecomunicacion), 166: 82-84 (2008).
4. C.O.S. Sorzano, J. M. Carazo. Avances en el procesamiento de imagenes biologicas a nivel microscopico. Bit (Revista del Colegio de Ingenieros de Telecomunicacion), 168: 72-75 (2008).
5. C.O.S. Sorzano, J. M. Carazo. Avances en el procesamiento de imagenes biologicas a nivel microscopico: Restauracion de imagenes. Bit (Revista del Colegio de Ingenieros de Telecomunicacion), 169: 62-63 (2008).
6. C.O.S. Sorzano, J. M. Carazo. Avances en el procesamiento de imagenes biologicas a nivel microscopico: Eliminacion de ruido. Bit (Revista del Colegio de Ingenieros de Telecomunicacion), 171: 69-72 (2008).
7. C.O.S. Sorzano, J. M. Carazo. Avances en el procesamiento de imagenes biologicas a nivel microscopico: Segmentacion. Bit (Revista del Colegio de Ingenieros de Telecomunicacion), 172: 71-74 (2008).
8. C.O.S. Sorzano, J.M. de la Rosa-Trevin, S. Jonic. High-throughput single-particle analysis in 3D electron microscopy. Prace Digest: 30-31 (2012)

Articles I will never publish

1. C.O.S. Sorzano, J. Vargas, A. Pascual-Montano. A survey of dimensionality reduction techniques.arXiv:1403.2877
2. C.O.S. Sorzano. COSS Notes on trading.
3. C.O.S. Sorzano, J.M. Carazo. Challenges ahead Electron Microscopy for Structural Biology from the image processing point of view. arXiv:1701.00326
4. C.O.S. Sorzano, D. Tabas-Madrid, F. Nuñez, C. Fernandez-Criado, A. Naranjo. Sample Size for Pilot Studies and Precision Driven Experiments. arXiv:1707.00222
5. C.O.S. Sorzano, E. Crisman, J.M. Carazo, R. León. Multitarget virtual screening for drug repurposing in COVID19. chemRxiv:12652997
6. C.O.S. Sorzano. The mathematics of contagious diseases and their limitations in forecasting. arXiv:2111.05727